Becton Dickinson and Company Limited

Nautilus Subsidiary, Inc.

Daniel Horner

Pierre F Indermuhle

David Stern

Ezra Van Gelder

Torri Elise Rinker

Vadim Lobanov

Ryan Kempston Seghers

Pengyu Hao

Matthew J Crow

Maryam Jouzi

Kevin Chen

Compositions, systems, and methods are disclosed for preparing and utilizing arrays, such as single-analyte arrays containing a plurality of fiducial elements with random spatial distributions. Arrays may be prepared with pluralities of fiducial elements comprising optically active or passive moieties. Arrays containing random spatial distributions of fiducial elements may be utilized for various array-based processes that require spatial information.

Integrated arrays for single-analyte processes

Aspects of the present disclosure include methods and systems for determining drop delay of a flow stream in a flow cytometer. Methods according to certain embodiments include obtaining a first frequency (f1) of drop perturbation of a flow stream subjected to an oscillating vibration, capturing one or more images of the flow stream in a detection field, obtaining a second frequency (f2) of drop perturbation of the flow stream based on one or more of the captured images and determining the drop delay of the flow stream based on the first frequency and the second frequency. Systems for practicing the subject methods having an imaging sensor for capturing one or more images of the flow stream and a processor configured to calculate drop delay using one or more of the captured images are also provided. Non-transitory computer readable storage mediums are also described.

Automated drop delay calculation

Growing community of inventors

Seattle, WA, United States of America

Daniel Horner