Mimedx Group, Inc.

Shriners Hospitals for Children

Shriners Hospital of Children

National Oilwell Varco, L.p.

Daniel Hernandez

Thomas J Koob

Mengyan Li

Douglas Pringle

Leon Paulos

Mei Niu

Jose Saldana

James R Streater

The disclosure describes methods of making high-strength NDGA collagen and associated methods of preparing collagen preparatory material and medical bioprostheses.

Methods of making high-strength NDGA polymerized collagen fibers and related collagen-prep methods, medical devices and constructs

Medical constructs with collagen fibers and gelatin and related collagen fibers. The collagen fibers can be derived from extruded soluble dermal collagen and can include a gelatin film attached to the at least one collagen fiber. The gelatin film can include one or more minerals and has a gelatin concentration of between about 0.1% to about 40% weight per volume.

Medical constructs including tubes and collagen fibers

Medical delivery devices include a needle and a flexible compressible impermeable tube attached to the needle. The compressible tube has an open interior channel. The device is adapted to releasably hold a length of a medical implant in the open interior channel of the tube. The medical implant can be slidably inserted into the interior channel of the tube and is loosely held by the tube.

Methods of using compressible tubes for placing implants

The disclosure describes methods of winding collagen fiber to make medical constructs and related collagen fiber tube and patch devices.

Methods of making collagen fiber medical constructs and related medical constructs, including tubes

Compressible tubes for placing implants and related medical kits and methods of using same

The invention relates to methods of treating mixtures containing polymeric materials, e.g., collagen, to form a polymer that intercalates into the polymeric material. The treatment provides greater tensile strength to the mixture, among other advantages. The polymer is formed of a monomeric unit having at least one catechol group that is oxidized to a quinone upon polymerization.

Growing community of inventors

Wesley Chapel, FL, United States of America

Daniel Hernandez