Biogen Idec Ma Inc.

Yale University

Daniel H S Lee

R Blake Pepinsky

John M McCoy

Sha Mi

Jane K Relton

Alexey Alexandrovich Lugovskoy

Ellen A Garber

Paul H Weinreb

Stephen M Strittmatter

Werner Meier

Dingyi Wen

Laura Silvian

Dinah W Y Sah

Xinzhong Wang

Dane S Worley

Sylvia A Rabacchi

Weiwei Li

John Mccoy

Dinah Y W Sah

Disclosed are immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are Nogo receptor antagonist polynucleotides. Also disclosed are compositions comprising, and methods for making and using, such Nogo receptor antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof, nucleic acids encoding the same and antagonist polynucleotides.

Nogo receptor antagonists and methods of increasing neurite outgrowth

The invention provides Sp35 polypeptides and fusion proteins thereof, Sp35 antibodies and antigen-binding fragments thereof and nucleic acids encoding the same. The invention also provides compositions comprising, and methods for making and using, such Sp35 antibodies, antigen-binding fragments thereof, Sp35 polypeptides and fusion proteins thereof.

NOGO receptor binding protein

Nogo receptor antagonists

Nogo receptor binding protein

Disclosed are immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are compositions comprising, and methods for making and using, such Nogo receptor antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same.

Growing community of inventors

Sudbury, MA, United States of America

Daniel H S Lee