Vanderbilt University

Daniel Frank Gochberg

Mark Does

Robert Adam Horch

Jeffrey S Nyman

In vivo methods for non-invasively imaging (or measuring without spatial localization) of neuro-electro-magnetic oscillations are achieved by a pulse sequence of radio frequency (RF) irradiation and magnetic field gradients. These RF and gradient pulses create an intermolecular zero-quantum coherence (iZQC), the frequency of which is: 1) controlled by one or more magnetic field gradients; and 2) made to match the frequency of the targeted neuro-electro-magnetic oscillation.

Magnetic resonance imaging of neuro-electro-magnetic oscillations

Systems and methods for characterizing bone structures are provided for characterizing bone structures. In the system and method, one or moreH NMR or MRI signals associated with a bone structure are obtained. Thereafter one or more signal parameters are computed from the obtained signals, where each of the signal parameters comprising at least one of a relaxation rate constant or a corresponding signal amplitude associated with a component of the obtained signals defined by a Tvalue or a range of Tvalues. Finally, the mechanical properties or fracture risk for the bone structure are determined based on the computed signal parameters and stored correlation data.

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Nashville, TN, United States of America

Daniel Frank Gochberg