3m Innovative Properties Company

Daniel E Duffy

Larry R Krepski

Joseph F Dellaria, Jr

David T Amos

Matthew R Radmer

William H Moser

Joan T Moseman

Bernhard M Zimmermann

Kyle J Lindstrom

John F Gerster

Philip D Heppner

Doris Stoermer

Luke T Dressel

John R Jacobsen

Joseph Dellaria

Imidazo ring systems substituted at the 1-position, pharmaceutical compositions containing the compounds, intermediates, methods of making the compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Substituted imidazo ring systems and methods

Imidazopyridine, imidazoquinoline, and imidazonaphthyridine compounds having an amide substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines

Imidazo-containing compounds (e.g., imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines) with an alkoxy substituent at the 1-position, pharmaceutical compositions containing the compounds and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

1-alkoxy 1H-imidazo ring systems and methods

Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.

Ether substituted imidazopyridines

Growing community of inventors

White Bear Lake Township, MN, United States of America

Daniel E Duffy