3m Innovative Properties Company

Radius Health, Inc.

Kindeva Drug Delivery, L.p.

Daniel Dohmeier

Ying Di Zhang

Gary Hattersley

Joan T Moseman

Lisa Dick

Ying Zhang

Alan Harris

Kenneth Brown

Jamal Saeh

Ehab Hamed

Joan Moseman

Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.

Formulations of abaloparatide, transdermal patches thereof, and uses thereof

A medical device comprising a composition comprising a therapeutically active amount of active agent, a zinc compound, and an array of microneedles. The zinc compound may be selected from the group consisting of zinc, pharmaceutically acceptable salts of zinc, and mixtures thereof. At least a portion of the composition is present as a coating on at least a portion of the microneedles. Methods of delivering a therapeutically active agent to a mammal using compositions of the disclosure are also included.

Zinc compositions for coated microneedle arrays

Growing community of inventors

White Bear Lake, MN, United States of America

Daniel Dohmeier