Globus Medical, Inc.

Amgen Inc.

Global Medical Inc.

Daniel Davenport

Chad Glerum

Duncan Sibson

Andrew Iott

Jason Gray

Mark Weiman

Colm McLaughlin

Mark Adams

Derek Martzall

Jason Pastor

Noah Hansell

Jody L Seifert

Sean S Suh

David C Paul

William S Rhoda

Jason Zappacosta

Mark Miccio

Marcin Niemiec

Ben Silber

Kevin Gahman

George Howard

Michael Zweizig

Robert Rhoads

Adam Friedrich

Jeff Bennett

Nick Padovani

Damien O'Halloran

Edward Dwyer

Douglas Cahill

Jamie Carroll

Vipin Kunjachan

Victoria Ferrari Alexander

Robert W Trout

Michelle Kofron

Ed Reilley

Brian Malm

Sheldon B Moberg

Ian B Hanson

Scott Robert Gibson

Paul F Bente, Iv

Margaux Frances Boyaval

Michael E Black

Kevin Lee Bokelman

Aditya Ingalhalikar

Khiem Pham

John Christian Love

John Matthews

Ryan Michael Agard

Daniel Shawn Codd

Mark Fromhold

Sean M O'connor

Rajan Ramaswamy

Matthew J Clemente

Scott Beaver

Mark A Destefano

Gautam N Shetty

Nicholas J Ciccarelli

Basel Hasan Taha

Robert Decker

Richard Castle

Kathleen Hill

John Gilbert

Matthew Bechtel

Milan George

Robert W Trout, Iii

Matt Bechtel

Nicholas D Padovani

Colm Mclaughlin

Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.

Drug delivery device, method of manufacture, and method of use

An implant for therapeutically separating bones of a joint has two endplates each having an opening through the endplate, and at least one ramped surface on a side opposite a bone engaging side. A frame is slideably connected to the endplates to enable the endplates to move relative to each other at an angle with respect to the longitudinal axis of the implant, in sliding connection with the frame. An actuator screw is rotatably connected to the frame. A carriage forms an open area aligned with the openings in the endplates. The openings in the endplates pass through the carriage to form an unimpeded passage from bone to bone of the joint. The carriage has ramps which mate with the ramped surfaces of the endplates, wherein when the carriage is moved by rotation of the actuator screw, the endplates move closer or farther apart.

Expandable intervertebral implant

Misaligned bones on opposite sides of a joint are aligned using a first rigid extension securable to one of the misaligned bones using a particular surgical approach, and a second rigid extension having a contacting surface positionable in contact with the other the two misaligned bones from the same surgical approach. The first and second rigid extensions are moved with respect to each other using a lever, whereby a pulling force is exerted on one of the bones, and a pushing force on the other, thereby aligning the first and second misaligned bones.

Aligning vertebral bodies

A soft tissue repair system is provided for covering or filling openings in the annulus of an intervertebral disc. The soft tissue repair system uses a single plug or a combination of a first plug and a second plug. The second plug is a flowable plug such as an adhesive material or a material that hardens to a flexible plug material. Each plug is configured to close the opening in the annulus and can be positioned within the opening, over the opening at the exterior surface or over the opening at the interior surface. The plug can also be combined with a clamping mechanism that engages the annulus to secure the plug in the opening.

Soft tissue repair system

A joint spacer for therapeutically maintains separation of bones of a joint. A frame defines a longitudinal axis extending between distal and proximal ends. A carriage is slideably retained within the frame and has at least one ramped surface and a threaded portion. An actuator screw is threadably engaged with the threaded portion, and bears against said frame to cause the carriage to slideably move within the frame when the actuator screw is rotated. A first endplate engages a bone of the joint, and has at least one ramped surface that is mateable with the ramped surface of the carriage.

An intervertebral spacer and stabilization implant includes a plate having sockets configured for retaining a fastener passable through the socket and into an adjacent vertebral body. One or more connecting projections extend from a side of the plate, to mate with projections extending from a spacer body. A plurality of teeth project from at least one of the upper or lower surfaces of the spacer body, and a chamber is formed through the spacer body to enable bone fusion between the vertebrae. The combined plate and spacer may be inserted to lie completely within the intervertebral space, or a portion of the plate may overlie a vertebral body.

Intervertebral implant

Expandable inter vertebral implant

An expandable fusion device is capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. The fusion device may include a body portion, a first endplate, and a second endplate, the first and second endplates capable of being moved in a direction away from the body portion into an expanded configuration or capable of being moved towards the body portion into an unexpanded configuration. The fusion device is capable of being deployed and installed in both configurations.

Expandable fusion device and method of installation thereof

Stand-alone interbody fusion devices and corpectomy devices suitable for use with an oblique implantation. The stand-alone interbody fusion devices may include a spacer having a substantially U-shaped body and a plate coupled to the spacer. The overall shape of the implant is asymmetrical such that a median plane, an oblique plane, or both planes divide the spacer and the plate into two asymmetrical halves. The implants are shaped and configured to allow for an oblique or anterolateral approach to the spine or an oblique corpectomy.

Interbody standalone intervertebral implant

Growing community of inventors

Collegeville, PA, United States of America

Daniel Davenport