Caliper Life Sciences, Inc.

Other

Singh, Rajendra

Ray, Sunetra

Ansaldi, Daniel

Daniel Ansaldi

Rajendra Singh

Ning Zhang

Sunetra Ray

Kevin P Francis

Stephen Oldfield

The disclosure features methods that include: administering to a subject a composition that includes particles, where each one of the particles features at least one targeting group that binds to a structural entity in the subject and at least one reacting group that reacts chemically with a reactive oxygen species in the subject, and where the particle emits luminescence when the reaction occurs; detecting the luminescence emission from the particles; and displaying an image of the subject showing locations of at least some reactive oxygen species in the subject based on the detected luminescence.

In-vivo reactive species imaging

Compositions and methods are described for normalizing a bioluminescent signal in a live animal.

Compositions and methods for in vivo evaluation of bioluminescence

Compositions and methods are described for detecting enzyme activity in a live organism (e.g., animal) are provided.

In vivo imaging of enzymatic activity

Growing community of inventors

Alameda, CA, United States of America

Daniel Ansaldi