University of California

Daniel A Low

Ke Sheng

Dan Ruan

Anand P Santhanam

James M Lamb

John S Ginn

Dylan O'Connell

A method and apparatus for removing breathing motion artifacts in imaging CT scans is disclosed. The method acquires raw imaging data from a CT scanner, and processes the raw CT imaging data by removing motion-induced artifacts via a motion model. Processing the imaging data may be achieved by initially estimating a 3D image to provide an estimate of raw sinogram image data, comparing the estimate to an actual CT sinogram, determining a difference between the sinograms, and iteratively reconstructing the 3D image by using the difference to alter the 3D image until the sinograms agree, wherein the 3D image moves according to the motion model.

Apparatus and method for removing breathing motion artifacts in CT scans

A system and method is provided for magnetic resonance imaging (MRI) guided respiratory gated radiotherapy using a respiratory motion model. MRI-guided respiratory gating is performed with a continuously updated model that represents a patient's internal anatomy as a mathematical function of an external respiratory surrogate. The motion model may be built and updated by acquiring images of a tissue in a subject and measuring, using the images, a position of the tissue in the images to determine motion of the tissue. The surrogate respiratory signal is acquired contemporaneously with acquiring the images. Motion of the tissue and the surrogate respiratory signal are correlated to create the motion model for the subject and gating a radiotherapy system may then be based upon the motion model. A multi-planar model-based respiratory gating may also be performed by sequentially imaging a stack of adjacent slice positions.

System and method for respiratory gated radiotherapy

In various embodiments, methods and devices are provided for generating a radiotherapy treatment plan for a subject to be implemented on a radiotherapy device. In certain embodiments the methods involve determining all feasible radiotherapy beam orientations free of collision for said radiotherapy device and said subject to provide a set of radiotherapy beam orientations; selecting from the set of all feasible radiotherapy beam orientations a subset of beams that meet treatment goals to be used in treatment of the subject to provide a selected beam set; calculating a navigation trajectory for the radiotherapy device to delivery said subset of beams to the subject where the trajectory is free of collision; and generating and writing instruction files to a tangible medium that can be executed by said radiotherapy device.

Growing community of inventors

Los Angeles, CA, United States of America

Daniel A Low