Massachusetts Institute of Technology

Daniel A Heller

Michael S Strano

Jong-Ho Kim

Jingqing Zhang

George W Pratt

Paul Walter Barone

Jinqing Zhang

A composition can include a complex, where the complex includes a photoluminescent nanostructure and a polymer free from selective binding to an analyte, the polymer adsorbed on the photoluminescent nanostructure, and a selective binding site associated with the complex.

Polymer-nanostructure composition for selective molecular recognition

Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described.

Systems and methods related to optical nanosensors comprising photoluminescent nanostructures

Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. Generally, the nanosensors comprise a photoluminescent nanostructure and a polymer that interacts with the photoluminescent nanostructure. In some cases, the interaction between the polymer and the nanostructure can be non-covalent (e.g., via van der Waals interactions). The nanosensors comprising a polymer and a photoluminescent nanostructure may be particularly useful in determining the presence and/or concentration of relatively small molecules, in some embodiments. In addition, in some instances the nanosensors may be capable of determining relatively low concentrations of analytes, in some cases determining as little as a single molecule. In some embodiments, the interaction between the analyte and the nanosensor (e.g., between the analyte and the photoluminescent nanostructure) can be reversible, which may allow, for example, for the reuse of a nanosensor after it has been exposed to an analyte.

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Rye Brook, NY, United States of America

Daniel A Heller