Other

New N.i. Medical (2011) Ltd

Itamar Medical Ltd.

N.i Medical Ltd.

Itamar Medical (c.m.) 1997 Ltd.

Daniel A Goor

Igor Granov

Evgeny Granov

Efim Frinerman

Raphael Mohr

Robert P Schnall

Jacob Sheffy

Peretz Lavie

William R Oliver

Ihsan A Haddad

A method and system are presented for use in assessment of at least one cardiac parameter of an individual. An electrodes arrangement is applied to an individual's body, for applying an electrical field to the body and providing an electrical output indicative of a systolic impedance change and of a velocity of said change during a cardiac cycle. Also provided is additional data indicative of at least of the following conditions of the individual: a value of total peripheral resistance (TPR), a value of cardiac index (CI), and existence of the AHF condition. Data corresponding to these condition is analyzed to determine whether the TPR satisfies a first predetermined condition and/or the CI satisfies a predetermined second condition and/or whether the acute heart failure (AHF) condition is identified, to thereby use the data indicative of the measured electrical output and selectively calculate said at least one cardiac parameter based on either the systolic impedance change data or on said data of the velocity of the impedance change.

Method and system for non-invasive measurement of cardiac parameters

A method and system are presented for use in determining a patient's heart condition. First and second data are provided, where the first data is indicative of the patient's heart rate, and the second data is indicative of bioimpedance peak value during a cardiac cycle. A relation between a certain predetermined value and a product of the first and said second data is determined, where such relation is indicative of the patient's left ventricular condition, enabling to identify a left ventricular dysfunction.

Method and system for use in monitoring left ventricular dysfunction

A method and apparatus for non-invasively determining a physiological condition. The method can include steps of monitoring peripheral arterial tone using an external sensor, detecting a change in the peripheral arterial tone, and determining the physiological condition when a specific change in the peripheral arterial tone has been detected. The physiological condition may be a cardiovascular disease state or endothelial dysfunction, for example. The apparatus can include a probe applied to a subject's digit for sensing peripheral arterial tone and outputting a corresponding signal, and a processor which processes the signal and provides an output from which the physiological condition can be determined or which determines the physiological condition based on the signal.

Method and apparatus for the non-invasive detection of medical conditions by monitoring peripheral arterial tone

A method and an apparatus for non-invasive detection of a physiological state or medical condition are disclosed. The method provides an indication of such state or condition such as myocardial ischemia or sleep apnea, by detecting the peripheral arterial tone's response to such state or condition, based on monitoring changes in peripheral arterial tone and determining that a change in the condition of the patient has occurred when a specific change in the peripheral arterial tone has been detected. A static pressure field is applied around the distal part of a digit of the subject. Peripheral arterial tone changes and related volume changes in the distal part of the digit are detected to thereby detect or monitor a physiological state or medical condition. The apparatus includes a finger probe (,), in the form of a tube (,) accommodating the patient's finger, which is designed to apply pressure, and a contiguous pressure cuff (,) which extends the boundary of the pressure field. The finger probe (,) either includes or is associated with a signal sensor/transducer (,).

An apparatus and method for detecting myocardial ischemia in a subject monitors the systemic vascular resistance of the subject and detects the presence of myocardial ischemia when the systemic vascular resistance increases by at least sixty percent over a base line value. Particular apparatus describe providing a measurement corresponding to the systemic vascular resistance of the cardiovascular system. A particular invasive pressure measuring apparatus uses a flexible catheter tube insertable into the artery of the subject and a micro-manometer embedded into the outer face of the wall of the catheter tube. The outer face of the embedded micro-manometer is directly exposed to the blood in an artery and the inner face of the embedded micro-manometer is covered by the inner face of the catheter tube wall.

Method and apparatus for detecting myocardial ischemia

A method and apparatus monitor myocardial ischemic events in various medical applications for providing continuous and contemporaneous information regarding, for example, modifying the amount of medication for a patient, determining response during (PTCA) balloon angioplasty, monitoring the onset of myocardial ischemic events during induction of anesthesia, determining painless myocardial ischemia in a resting patient, and monitoring the onset of myocardial ischemic during stress conditions in a patient. The method and apparatus also provide a calibration method for determining from a Resistive Index and using the resulting transformation for calculating, on a continuing basis, both systemic vascular resistance and cardiac output.

Diagnostic methods and apparatus employing monitoring of myocardial

In the described method and apparatus for examining a subject's cardiovascular system, a blood-pressure signal having a waveform varying in accordance with the subject's arterial pressure is differentiated to produce a dP/dt signal having a waveform varying in accordance with the rate at which the blood-pressure signal varies. The pressure at the time of the peak dP/dt signal is detected and is divided by the dP/dt signal to produce a measurement corresponding to the systemic vascular resistance. The latter measurement is then multiplied by a resistance factor corresponding to the physical resistance characteristic of the particular cardiovascular system examined. A measurement of the cardiac output may also be produced by subtracting, from the mean arterial pressure of the subject, the subject's central venous pressure and dividing the latter by the systemic vascular resistance.

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Tel Aviv, Israel

Daniel A Goor