Danisco US Inc.

Danfeng Song

Michael C Ward

Richard Ray Bott

Michael D Ward

Wei Xu

Susan Mampusti Madrid

Jing Ge

Xiaogang Gu

Benjamin S Bower

Ling Hua

Mingmin Song

Jimmy Chan

Steven Sungin Kim

Zhengzheng Zou

Zhongmei Tang

Zhen Qian

Zhiyong Xie

Bo Zhang

Steven Sungjin Kim

Guoqing Liu

Michael Ward

Compositions and methods are provided for genome modification at a target site in the genome of a filamentous fungal cell. The methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for modifying or altering the target site. Aspects in which the filamentous fungal cell being modified has a defective non-homologous end joining pathway are also provided.

Fungal genome modification systems and methods of use

Compositions and methods are provided for genome modification at a target site in the genome of a fungal cell. The methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for promoting modification of the DNA sequence at a target site in a fungal host cell genome.

Compositions and methods are provided for genome modification at a target site in the genome of a fungal cell. Aspects of methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for promoting insertion of a donor DNA at a desired target site in a fungal host cell genome.

Growing community of inventors

Palo Alto, CA, United States of America

Danfeng Song