Recyte Therapeutics, Inc.

Sanford-burnham Medical Research Institute

Biotime, Inc.

Mandala Biosciences, LLC

Dana Larocca

Paola A Bignone

Mohammad Hassanipour

Michael D West

Evan Y Snyder

Midori Greenwood-Goodwin

Jiwei Yang

Provided herein are cells and methods for reprogramming iPS cells from a supercentenarian and their differentiated derivatives having differences from non-supercentenarian iPS derived cells that contribute to disease resistance and longevity. Additionally, provided herein are methods for treatment and prevention of age related diseases by administration of therapeutic sciPS derived cells or cell derived reagents. Also provided herein, are methods for identifying reagents for treatment of age related diseases using sciPS cell-based assays.

Supercentenarian induced pluripotent stem (sciPS) cells and methods of making and using thereof

The invention provides methods, compositions, uses and kits relating to exosomes isolated from progenitor cells.

Exosomes from clonal progenitor cells

The invention provides methods, compositions and kits for making and using pericyte-like cells or perivascular stromal cells derived from pPS cells.

Perivascular stromal cells from primate pluripotent stem cells

The invention provides methods, compositions and kits for the identification and enrichment of progenitor cell lines obtained from pluripotent stem cells.

Growing community of inventors

Alameda, CA, United States of America

Dana Larocca