Janssen Pharmaceutica Nv

Verno Holdings, LLC

Other

The Scripps Research Institute

Ortho-mcneil Pharmaceutical Corp.

Dana L Johnson

John D Riley

Robert W Tuman

Jan L Sechler

Heather Rae Hufnagel

Richard William Connors

Robert A Galemmo

Harry Patrick Barnum

Tianbao Lu

Donald William Ludovici

Kristi A Leonard

Maxwell David Cummings

Thomas P Markotan

Stuart Emanuel

Linda K Jolliffe

Richard Scott Alexander

Jay Mei

Christian Andrew Baumann

Anna C Maroney

Zhihua Sui

Jeremy Mark Travins

Xuqing Zhang

Chih Yung Ho

Robert A Galemmo, Jr

Ian A Wilson

Umar Maharoof

Michael Gaul

Eric D Strobel

Ehab Khalil

Cuifen Hou

Enrico A Stura

Oded Livnah

Hwa Kwo Yen

Bengt Anders Brunmark

Carl R Illig

Mark James Wall

Sanath K Meegalla

Li Liu

Kevin Douglas Kreutter

Jinsheng Chen

Guozhang Xu

Steven J Coats

Shelley K Ballentine

Carlos Plata-Salaman

Bart L De Corte

Kenneth J Wilson

Alexander Y Kim

Virginia L Smith-Swintosky

M Jonathan Rudolph

Mark J Schulz

Robert Allan Zivin

Barry Fegely

Nand Baindur

David Breslin

Umar S M Maharoof

Francis Farrell

Michael Renzi

Saneth Meegalla

Jingsheng Chen

Kenneth Wilson

Heather Rae Hufnagal

Glasses holder apparatus

A process for decontaminating a fluid and recovered vapor, particularly processing and recycling contaminated water, utilizing a vaporizer-desalination unit to separate a contaminated water flow into a contaminated disposal flow and a clean water vapor flow. The contaminated disposal flow may be dried and separated into recovered minerals utilizing heat from the clean water vapor flow to dry the contaminated disposal flow.

Process for decontaminating water and generating water vapor

A system and method for decontaminating a fluid and recovered vapor, particularly processing and recycling water used in an oil zone steam process, utilizing a vaporizer-desalination unit to separate a contaminated water flow into a contaminated disposal flow and a clean water vapor flow. The contaminated water flow is recovered after separation from a combined oil and water flow from an oil well. The clean water vapor flow is preferably passed through a steam generator to produce the steam used in the oil zone steam process. The steam is injected into the oil zone of a designated well and then extracted as the combined oil and water flow. Once primed with sufficient external water, the system and method is designed to operate continuously with minimal replenishment because of the water/vapor/steam cycle.

System for decontaminating water and generating water vapor

A system and method for decontaminating a fluid and recovered vapor, particularly processing and recycling contaminated water, utilizing a vaporizer-desalination unit to separate a contaminated water flow into a contaminated disposal flow and a clean water vapor flow. The contaminated disposal flow may be dried and separated into recovered minerals utilizing heat from the clean water vapor flow to dry the contaminated disposal flow.

A system for processing a fluid by generating water vapor through forced compression and rotation in a vessel includes capturing sea water for use in desalination processing in the vessel. Any fluid processed in the vessel, including sea water, can be used to create water vapor that rises to an elevation under its own power. After condensing the water vapor to liquid again, the condensed liquid falls upon a hydro-electric generator to generate electricity that is stored for later use. Brine output from the system can be recycled for re-processing through the system to increase water vapor yield. The wet brine output may also be dried to produce dried brine for subsequent processing of salt and other minerals.

System for processing water and generating water vapor for other processing uses

Salon dryer chair

A system and method for processing a fluid, including decontaminating water and generating water vapor includes introducing the fluid into a vessel. The fluid is moved through a series of rotating trays alternately separated by stationary baffles so as to swirl and heat the fluid to effect the vaporization thereof to produce a vapor having at least some of the contaminants separated therefrom. The vapor is removed from the vessel for condensing apart from the separated contaminants and the remaining water. The vapor may be passed through a turbine connected to an electric generator. Sensors in a controller may be employed to adjust the speed of rotation of the trays or fluid input into the vessel in response to the sensed conditions. The treated fluid may be recirculated and reprocessed through the vessel to increase the purification thereof.

A system and method for decontaminating water and generating water vapor includes introducing contaminated water in to a vessel. The water is moved through a series of rotating trays alternately separated by stationary baffles so as to swirl and heat the water to effect the vaporization thereof to produce a vapor having at least some of the contaminants separated therefrom. The vapor is removed from the vessel for condensing apart from the separated contaminants and the remaining water. The vapor may be passed through a turbine connected to an electric generator. Sensors in a controller may be employed to adjust the speed of rotation of the trays or water input into the vessel in response to the sensed conditions. The treated water may be recirculated and reprocessed through the vessel to increase the purification thereof.

The invention is directed to a method of inhibiting FLT3 tyrosine kinase activity or expression or reducing FLT3 kinase activity or expression in a cell or a subject comprising the administration of a farnesyl transferase inhibitor and a FLT3 kinase inhibitor selected from compounds of Formula I': Included within the present invention is both prophylactic and therapeutic methods for treating a subject at risk of (or susceptible to) developing a cell proliferative disorder or a disorder related to FLT3.

Synergistic modulation of FLT3 kinase using a FLT3 inhibitor and a farnesyl transferase inhibitor

The present invention comprises compounds of Formula (I): wherein: X, R, R, R, and Rare as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).

4-Azetidinyl-1-phenyl-cyclohexane antagonists of CCR2

The present invention comprises compounds of Formula (I). wherein: R, R, R, and Rare as defined in the specification. The invention also comprises pharmaceutical compositions comprising the compounds of formula (I) and methods of preventing, treating or ameliorating a CCR2 mediated syndrome, disorder or disease, for example, type II diabetes, obesity or asthma, by administering the compounds of formula (I).

4-azetidinyl-1-heteroaryl-cyclohexanol antagonists of CCR2

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Upper Black Eddy, PA, United States of America

Dana L Johnson