Gilead Sciences, Inc.

Dana J Levine

Winston C Tse

Anna Chiu

Stephen R Yant

Dimitrios Stefanidis

Tomas Cihlar

Eric Gorman

Charles William Rowe

Elena Bekerman

Wade S Blair

Jim X Zheng

Laura Elizabeth Bauer

Andrew Stephen Mulato

Martin Sunkwang Rhee

Scott P Sellers

Eric M Gorman

The present disclosure relates to compounds of Formula (Ia) and (Ib): or a pharmaceutically acceptable salt thereof, which are useful in the treatment of an HIV infection in heavily treatment-experienced patients with multidrug resistant HIV infection.

Capsid inhibitors for the treatment of HIV

The present disclosure provides methods of preventing HIV in a subject, comprising administering to the subject a therapeutically effective amount of a compounds of Formula (Ia) or (Ib): or a pharmaceutically acceptable salt thereof, optionally in combination with one or more additional therapeutic agents. Methods of reducing the risk of acquiring HIV (e.g., HIV-1 and/or HIV-2) are also provided.

Capsid inhibitors for the prevention of HIV

Growing community of inventors

San Leandro, CA, United States of America

Dana J Levine