Zhejiang University

Dan Wu

Yi Zhang

Hongxi Zhang

Ruibin Liu

Donghong Liu

Tian Ding

Enbo Xu

Mofei Shen

Xingwang Yong

Tingting Liu

Haotian Li

A CEST data fitting method and apparatus based on an extrapolated semisolid magnetization transfer reference signal, and a medium, which belong to the field of magnetic resonance imaging. According to the CEST data fitting method based on an extrapolated semisolid magnetization transfer reference signal, a lineshape of an MT effect is fused into a Bloch-McConnell equation, the MT effect can be obtained by means of fitting a model that is represented by the equation, and an interference effect can be eliminated by calculating the difference between a curve that is obtained via fitting and a curve that is collected from an experiment. The Bloch-McConnell-based fitting method can take into consideration a radio frequency pulse waveform that is actually used in an experiment, and can also be used when a system is not in steady state.

CEST data fitting method and apparatus based on extrapolated semisolid magnetization transfer reference signal, and medium

A method for 3D oscillating-gradient prepared gradient spin-echo imaging and a device. The imaging method comprises the following steps: first, using a global saturation module to destroy previous residual transverse magnetization; second, embedding a pair of trapezoidal cosine oscillating gradients into a 90°-180°-90°radiofrequency pulse by a diffusion encoding module, to separate diffusion encoding from signal acquisition; then, using a fat saturation module to suppress a fat signal; finally, acquiring a signal by means of gradient spin-echo readout, and correcting phase errors among multiple excitations by multiplexed sensitivity-encoding reconstruction. Compared with a 2D plane echo-based oscillating gradient diffusion sequence used on a 3T clinical system, a 3D oscillating-gradient prepared gradient spin-echo sequence effectively reduces the imaging time, improves the signal to noise ratio, and is beneficial to clinical transformation of time-dependent diffusion MRI technology.

3D oscillating gradient-prepared gradient spin-echo imaging method, and device

Disclosed are a zirconium-based metal-organic framework material and a preparation method thereof. Plasma-activated water or strong acid electrolyzed water is added to a raw material system for preparing a zirconium-based metal-organic framework material UiO-66, and they are then subjected to a reaction to obtain a crude product. The crude product is subjected to a post-treatment to obtain the zirconium-based metal-organic framework material UiO-66.

Zirconium-based metal-organic framework material and preparation method thereof

Disclosed is a method and apparatus for frequency drift correction of magnetic resonance CEST imaging, and a medium and an imaging device. The method comprises the following steps: firstly, in the frequency drift correction module, exciting a target slice by using a small flip-angle radio-frequency pulse, and acquiring a single line of free induction decay signals or two lines of non-phase encoding gradient echo signals; secondly, respectively calculating a value of the main magnetic field frequency drift according to phase information and an acquisition time of the single line of free induction decay signals or the two lines of non-phase encoding gradient echo signals; then adjusting the center frequency of the magnetic resonance device in real time according to the calculated value of the main magnetic field frequency drift, and achieving the real-time correction of main magnetic field frequency drift; and finally, performing CEST imaging.

Method and apparatus for frequency drift correction of magnetic resonance CEST imaging, and medium and imaging device

The present disclosure provides a method for optimizing T1-weighted magnetic resonance imaging of infant brains. Firstly, T1 and PD maps of infant brains at 0-12 months old are collected to obtain average T1 and PD values of WM and GM of the infant brains, and infants are classified into three age groups according to the characteristics of WM and GM T1 values of the infant brains. Then, the theoretical signal strength of the WM and GM of the infant brains generated from a 3D T1-weighted imaging sequence is calculated through Bloch simulation, and a theoretical optimal TI scheme of each group is determined according to the simulated WM/GM contrast characteristics under different TIs. Finally, the theoretical optimal TI scheme is applied to a target infant brain according to the designated age group for 3D T1-weighted magnetic resonance imaging.

Method for optimizing T1-weighted magnetic resonance imaging of infant brain

A magnetic resonance CEST imaging sequence and device based on a frequency stabilization module are provided. It includes following steps: first, in the frequency stabilization module, exciting a target slice with a small-flip-angle radio frequency pulse, and collecting three lines of non-phase-encoded k-space data; second, obtaining an estimated value of the frequency drift of the main magnetic field by calculating the phase difference between the three lines of non-phase encoded k-space data; third, adjusting a center frequency of the radio frequency pulse based on the calculation result of the frequency drift of the main magnetic field, to realize a real-time correction of the frequency drift of the main magnetic field; and fourth, performing conventional magnetic resonance CEST imaging.

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Hangzhou, China

Dan Wu