Cinclus Pharma Holding Ab (publ)

Shenzhen University

Dan Wang

Mikael Hillgren

Thomas Larsson

Kjell Jarring

Lu Wang

Kaishun Wu

Yongpan Zou

Jinyong Wu

Xingbang Lin

The present invention relates to polymorphs of the hydrochloride salt of 5-{2-[({8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-yl}carbonyl)-amino]ethoxy}-5-oxopentanoic acid (linaprazan glurate), more specifically Form 1 and Form 2 of the HCl salt of linaprazan glurate. The invention also relates to a process for the preparation of such polymorphs, to pharmaceutical compositions comprising such polymorphs, and to the use of these polymorphs in the treatment or prevention of gastrointestinal inflammatory diseases or gastric acid related diseases, in particular erosive gastroesophageal reflux disease (eGERD).

Polymorphs of the hydrochloride salt of linaprazan glurate

The invention relates to a limb movement gesture judgment method, which comprises the following steps: a plurality of sensors worn on a moving wrist output induction signals generated by the sensors, and a data packet is formed and sent; the overall state of the multiple induction signals in the received data packet is compared with pre-stored movement type templates, so that the movement type of the moving wrist is determined; standard parameters of the sensor data about the movement type are obtained and separately compared with the multiple received sensor data, whether the movement gesture of the moving limb is normal or not is judged according to the degree of deviation of one or more induction signals from the corresponding standard parameters, and a corresponding prompt message is provided; wherein, the induction signals include a direction acceleration signal, a direction angle acceleration induction signal, and a pressure induction signal. The limb movement gesture judgment method and device have the following beneficial effects of being free of time and place limitations and low in cost.

Limb movement gesture judgment method and device

Growing community of inventors

Guangdong, China

Dan Wang