Dune Medical Devices Ltd.

Dilon Medical Technologies Ltd.

Dune Medical Ltd.

Dan Hashimshony

Gil Cohen

Iddo Geltner

Gal Aharonowitz

Orit Yarden

Harel Golombek

A graphical user interface (GUI) including: (a) a group definition module adapted to accept a user input defining groups; (b) a data receiver operable to receive a plurality of individual measurement input datum indicative of status of a substrate; (c) a grouping module configured to assign each of said individual measurement input datum to one of said groups to produce grouped data; and (d) an output module adapted to output the grouped data.

Graphical user interfaces (GUI), methods and apparatus for data presentation

A sensor unit for use in measurements on a subject is presented. The sensor unit includes a near field electromagnetic sensor and a flexible signal transmission structure, which are integral with one another by means of at least one common continuous surface. The flexible signal transmission structure is constructed from a first layer including signal connection lines associated with sensor cells near field electromagnetic sensor and a second electrically conductive layer electrically coupled to the electrically conductive material of the sensor.

Electromagnetic sensor for use in measurements on a subject

A medical device is presented for use in tissue characterization and treatment. The device comprises a tissue characterization probe comprising an elongated carrier carrying an array of tissue characterization sensors which are arranged in a spaced-apart relationship on at least a part of the carrier with known distances between them along a longitudinal axis of the carrier and along at least part of a circumference of the carrier, such that during progression of the probe through a tissue mass each of the sensors generates tissue characterization signals from successive locations thereof within the tissue mass enabling to locate an abnormal tissue inside said tissue mass, thereby enabling consequent treatment of the abnormal tissue. Several movement mechanisms are described for enabling relative movement between the carrier and a treatment tool passing therethrough.

Medical device and method for use in tissue characterization and treatment

A medical device is presented for use in tissue characterization and treatment. The device comprises: a tissue characterization probe comprising an elongated carrier for carrying an array of tissue characterization sensors arranged in a spaced-apart relationship at least along an axis of said carrier, such that progression of the probe through a tissue mass provides for locating and determining a dimension of an abnormal tissue specimen inside said tissue mass based on characterization signals from the sensors in the array, thereby enabling consequent treatment of the abnormal tissue specimen by a treatment tool.

A medical device including a tissue characterization probe having an elongated carrier for carrying an array of tissue characterization sensors arranged in a spaced-apart relationship at least along an axis of said carrier within at least a distal portion thereof, such that progression of the probe through a tissue mass provides for locating and determining a dimension of an abnormal tissue specimen inside said tissue mass based on characterization signals from the sensors in the array. The elongated carrier has two integral portions including said distal portion and a hollow portion extending between a proximal end of the carrier and said distal portion. The carrier is configured for passing a predetermined treatment tool through the hollow portion thereof and enabling at least a part of the treatment tool to project from the hollow portion and extend along the distal portion.

The present invention relates to a device for tissue-characterization, designed for effective sensor-to-tissue contact. The device includes an element, having a rigid surface of a linear cross-section, on which at least one sensor is arranged, and a mechanism for applying a force to a soft tissue, the line of force being at an acute angle with the rigid surface, for stretching or stretching and pushing the soft tissue against the rigid surface, thus achieving effective contact between the tissue and the at least one sensor. In consequence, the accuracy of the sensing is improved. In accordance with another embodiment, a plurality of sensors is employed, arranged along a curved element, for providing three-dimensional information regarding the tissue, for example, by small-scale computerized tomography.

Tissue-characterization probe with effective sensor-to-tissue contact

A surgical tool for use in a tissue removal procedure from a subject is described. The surgical tool has proximal and distal regions and at least one sensor for sensing one or more predetermined conditions located at a distal region of the surgical tool. And a substantially flat signal transmission structure electrically connected with the at least one sensor and extending between the location at the distal region and the proximal region. The signal transmission structure is configured for providing impedance controlled signal transmission between the at least one sensor and the proximal region.

Surgical tool

A medical device is presented for use in tissue characterization and treatment. The device comprises: a tissue characterization probe comprising an elongated carrier carrying an array of tissue characterization sensors arranged in a spaced-apart relationship at least along an axis of said carrier, such that progression of the probe through a tissue mass provides for locating and determining a dimension of an abnormal tissue specimen inside said tissue mass based on characterization signals from the sensors in the array, thereby enabling consequent treatment of the abnormal tissue specimen by a treatment tool.

A method, apparatus and probe for examining tissue for the presence of target cells, particularly cancerous cells, by subjecting the tissue to be examined to a contrast agent containing small particles of a physical element conjugated with a biological carrier selectively bindable to the target cells. Energy pulses are applied to the examined tissue. The changes in impedance and/or optical characteristics of the examined tissue produced by the applied energy pulses are detected and utilized for determining the presence of the target cells in the examined tissue. In a described preferred embodiment, the applied energy pulses include laser pulses, and the physical element conjugated with a biological carrier is a light-sensitive semiconductor having an impedance which substantially decreases in the presence of light. The same probe used for detecting the targeted cells may also be used for destroying the cells so targeted.

Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus

A probe device for use in a tissue inspection system is presented. The probe device comprises a probe body and a control unit at least partially incorporated in the probe body. The probe body carries at least a tissue characterization unit operable for providing sensing data indicative of at least one tissue property at measurement locations in the tissue portion being held by the probe. The control unit comprises: a processor utility for receiving and processing the sensing data and generating measured data indicative of a spatial profile of said at least one tissue property distribution within the tissue portion, and comprises at least one of the following: an imaging utility for receiving said measured data and generating and displaying an image indicative thereof thereby enabling a user to select a region of said tissue portion for further analysis; and a pattern generator module configured for receiving and analyzing said measured data and determining a pattern indicative of an arrangement of regions in said tissue portion, thereby enabling selection of at least one of the regions for further analysis.

Tissue sampling for pathological study

A mapping system () including: (a) at least one external marker () adapted for positioning outside a target () to define a target context; (b) at least one target marker () adapted for positioning with the target; (c) a data acquisition tool () configured to provide position coordinates for at least one data point () at the target (); and (d) a registration module () adapted to output position coordinates of said at least one data point relative to at least a portion of the target context.

Mapping system and method for mapping a target containing tissue

A device for tissue characterization, comprises a structure; a first mechanism, associated with the structure, configured for exerting a first force on a tissue, for fixing the tissue to the structure, so as to substantially immobilize the tissue; and a second mechanism, associated with the structure, configured for pressing a sensor against an external surface of the immobilized tissue, thereby exerting a second force on the immobilized tissue, wherein at least a component of the first force is in opposition to at least a component of the second force, forcing the immobilized tissue against the sensor, and forcing the sensor against the immobilized tissue, bringing about an effective contact between the sensor and the immobilized tissue.

Device for forming an effective sensor-to-tissue contact

A device and method are provided for tissue handling, while maintaining the in-vivo tissue orientation. The device includes a structure, configured for receiving and holding a tissue specimen, wherein the tissue specimen includes tissue positional references; and device positional references, associated with the structure, for fixing the orientation of the tissue specimen, when held by the device, so as to reflect the tissue specimen positional references.

Growing community of inventors

Givat Ada, Israel

Dan Hashimshony