Tel Aviv University

The Brigham and Women's Hospital, Inc.

Ramot University Authority for Applied Research and Industrial Development Limited

Id Biomedical Corporation of Quebec

Dan Frenkel

Dorit Farfara

Beka Solomon

Uri Oron

Nofit Borenstein

Howard L Weiner

Ruth Maron

Hana Tuby

Veronica Lifshitz

Hilit Levy

Dorit Trudler

Adi Kopelevich

Tali Benromano

Eilat Hanan

Methods for treating and reducing risk of cerebral amyloid angiopathy (CAA) using nasal vaccination with a proteosome adjuvant.

Methods of treating cerebral amyloid angiopathy

Methods and systems are provided for delivering visible or infrared biostimulatory energy to bone marrow to subjects having or developing Alzheimer's disease. The radiation is delivered to sites remote from the brain at a dose sufficient to cause stimulated mesenchymal stem cells to appear in the brain and degrade &#x3b2;-amyloid. The energy may be coherent light and can be administered transcutaneously, subcutaneously, or via an intramedullary probe.

Low level laser therapy for Alzheimer's disease

Low level laser therapy for alzheimer's disease

An insulin degrading enzyme (IDE) inhibitor for use in the treatment of a disease selected from the group consisting of an autoimmune disease of the central nervous system and a neurodegenerative disease is disclosed.

Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases

Use of an isolated peptide comprising an amino acid sequence being no more than 25 amino acids in length, the amino acid sequence comprising at least one aspartate or a homolog thereof, the peptide having an Insulin-Degrading Enzyme (IDE) inhibitory activity, for the manufacture of a medicament identified for treating a disease selected from the group consisting of diabetes, obesity, hyperglycemia, retinal damage, renal failure, nerve damage, microvascular damage and varicella-zoster virus (VZV) infection is disclosed.

Peptides, pharmaceutical compositions comprising same and uses thereof

A method of immunizing against plaque forming diseases using display technology is provided. The method utilize novel agents, or pharmaceutical compositions for vaccination against plaque forming diseases which rely upon presentation of an antigen or epitope on a display vehicle. The method further includes agents, or pharmaceutical compositions for vaccination against plaque forming diseases, which rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, disaggregation of plaques results from the immunization.

Bacteriophage displaying a&#x3b2; epitopes and method of use

A strategy for immunizing against amyloid plaques using display technology. The strategy includes methods, agents, and pharmaceutical compositions for vaccination against plaque forming diseases (e.g. Alzheimer's disease) which rely upon presentation of an antigen or epitope on a display vehicle. The strategy further includes methods, agents, and pharmaceutical compositions for vaccination against plaque forming diseases (e.g. Alzheimer's disease) which rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, desegregation of plaques results from the immunization.

Filamentous bacteriophage displaying an &bgr;-amyloid epitope

Growing community of inventors

Rehovot, Israel

Dan Frenkel