Pfizer Corporation

Damien Webb

Michael Aaron Brodney

Lei Zhang

Christopher Ryan Butler

Christopher John Helal

Erik Alphie LaChapelle

Laura Ann McAllister

Qingyi Yang

Natasha Mariam Kablaoui

The present invention provides, in part, compounds of Formula I: or an N-oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: X, X, R, R, m and n are as described herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds, N-oxides, or salts, and their uses for treating M4-mediated (or M4-associated) disorders including, e.g., Alzheimer's Disease, Parkinson's Disease, schizophrenia (e.g., its cognitive and negative symptoms), pain, addiction, and a sleep disorder.

Piperazine azaspiro derivatives

Growing community of inventors

Bottminggen, Switzerland

Damien Webb