Ion Beam Applications S.a.

Université Libre De Bruxelles

Technische Universitát Dresden

Helmholtz-zentrum Dresden-rossendorf E.v.

Damien Prieels

Yves Claereboudt

Julien Smeets

Yves Jongen

Guntram Pausch

Caterina Brusasco

Frédéric Stichelbaut

Bruno Marchand

Alexandre Debatty

Guillaume Janssens

Christian Golnik

Wolfgang Enghardt

Alain Dubus

Jean-Claude Dehaes

Victor Breev

Martin Arnold

Jean-François De Le Hoye

Fernando Hueso-Gonzalez

The present disclosure relates to a particle therapy system for irradiating a target with a scanning beam technique. In one implementation, the system includes an irradiation planning device with a planning algorithm configured to associate a particle beam energy E(i) to each spot of the irradiation plan and organize the spots in a sequence of spots according to energy. The system may further include a control system configured for controlling in parallel, from spot to spot, a variation of an output energy of a beam generator, a variation of a magnetic field of one or more electromagnets of a beam transport system and a variation of a magnetic field of the scanning magnet.

Particle therapy system and method with parallel control of energy variation and beam position variation

The present invention relates to a dosimetry device for an energy particle beam from a source and including at least two ionization chambers, each of which includes a collector electrode and a polarization electrode, said electrodes in each ionization chamber being separated by a gap including a fluid, an energy beam from a single source passing through said ionization chambers, the device being characterized in that said ionization chambers have different charge collection efficiency factors. Said calculation algorithm for the dose rate deposited by said beam is based on the measurement of an output signal in each ionization chamber of the device and on a &#x25a1;gain&#x25a1; factor related to a first ionization chamber, said &#x25a1;gain&#x25a1; factor being theoretically predetermined on the basis of said intrinsic and/or extrinsic parameters of said ionization chambers.

Device and method for measuring an energy particle beam

The invention is related to a method for monitoring a range of a particle beam in a target. The method is using gamma detectors for detecting prompt gammas produced in the target. The time differences between the time of detecting a gamma quantum and a time of emission of a particle or a bunch of particles from the radiation device are determined. A statistical distribution of those time difference is used to deduce information related to the range of the beam. The invention is also related to an apparatus for monitoring a range based on measured time profiles of detected prompt gammas.

Method and apparatus for monitoring the range of a particle beam

The invention is related to a method and apparatus for verifying the beam range in a target irradiated with a charged hadron beam, such as a proton beam. The beam range is the location of the Bragg peak in the target, being the location where the largest portion of the dose is delivered. The method utilizes a prompt gamma camera provided with a slit-shaped opening, so as to be able to produced a 1-dimensional profile of the dose distribution along the beam line. The camera is mounted with the slit oriented perpendicularly to the beam line. The method comprises the steps of calculating a position of the camera with respect to a target, for a plurality of beam energies and spots to be irradiated. The method further comprises the steps of verifying the beam range for said plurality of spots, and delivering a value representative of the difference between the estimated beam range and the actual beam range. The apparatus of the invention is provided with a positioning module for positioning the camera.

Method and apparatus for particle beam range verification

A charged hadron therapy system for delivering charged hadron radiation to a target is provided. The system comprises a target positioning couch for supporting the target being moveable along a translation direction and a beam delivery system comprising a beam scanning means for scanning a hadron pencil beam over said target in a first scanning direction and a second scanning direction being substantially parallel with the translation direction. The beam scanning means is limited for providing a maximum scanning amplitude AY in the second scanning direction. The system comprises an irradiation controller configured for simultaneously and synchronously performing the moving of the couch and the scanning, so as to deliver charged hadron radiation to a target over a target size being larger in the Y direction than the maximum scanning amplitude AY.

Charged hadron beam delivery

The invention is related to an apparatus and method for charged hadron therapy verification by detecting and/or quantifying prompt gammas produced when irradiating a target () with a charged hadron beam. The apparatus comprises a collimator () provided with a slit-shaped portion () configured to be arranged perpendicularly to the beam line and facing the target, a detection means () suitable for detecting said prompt gammas and a calculation and representation means. In the apparatus and method of the invention, the slit is configured to allow the passage of prompt gammas emitted from a range of depths in said target (), said depths being measured in the direction of the charged hadron beam. Furthermore, said detection means is configured to detect prompt gammas emitted from each location within said range, and said calculation and representation means is configured to derive from a detected prompt gamma a value representative of the dose at the location from where said prompt gamma is emitted, and to represent a dose-related distribution for a plurality of locations within said range.

Apparatus for particle therapy verification

A device and method for on line dosimetry monitoring of a hadron beam generated from a source of radiation and delivered to a target, the device comprising a plurality of support plates arranged in parallel in a face-to-face relation, separated from each other by gas filled gaps and perpendicularly to the central axis of said hadron beam, and forming a plurality of ionization chambers, each support plate having on a first side one or more collecting electrodes and on a second side one or more high voltage electrode, arranged in such a way that each support plate has said first side substantially opposed to said second side of another support plate. Each support plate has an opening so as to form an inner cavity for allowing the undisturbed passage of a central portion of the hadron beam delivered to said target and a peripheral region for intercepting and measuring, by means of said plurality of ionization chambers, a peripheral portion of said hadron beam.

Device and method for online quality assurance in hadron therapy

The present invention relates to a detector for measuring characteristics of an energetic particle beam generated by a radiation source, the detector including means to vary the incoming particle beam energy; a plurality of sensors arranged in parallel; and processing means capable of processing signals coming from said sensors in correlation with said energy variation.

Device and method for measuring characteristics of An Ion beam

An irradiation apparatus for irradiating by scanning a target volume according to a predetermined dose profile with a scanning beam of charged particles forming an irradiation spot on said target volume, said apparatus comprising:

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Court-Saint-Etienne, Belgium

Damien Prieels