Valorisation-recherche, Limited Partnership

Valorisation Hsj, Limited Partnership

Plant Advanced Technologies Pat

Temisis

Damien Boeglin

Sylvain Chemtob

Florian Sennlaub

William A Lubell

Huy Ong

Caroline Proulx

Zohreh Sajjadi

David Sabatino

Frédéric Bourgaud

Pierre Warnault

Benoît Mignard

Paul Hannewald

The present invention thus relates to amide derivatives of polysubstituted quinic acids (abbreviated to 'QPS'), of general formula (IA): (IA), in which &#x2014;Rand Rare, independently of one another: H, with the proviso that Rand Rare not both a hydrogen atom, a butyl group, a C-Calkyl group, &#x2014;a C-Calkylaryl or arylalkyl group, or a C-Caryl group; and &#x2014;Q, Q, Qand Qare, independently of one another, an OH, caffeoyl, maloyl, caffeoylmaloyl ou maloylcaffeoyl group, with the proviso that at least one of these radicals is not an OH group, or to a pharmaceutically acceptable salt or stereoisomer or hydrate thereof, and also to the process for producing same, to the use thereof as a medicament, in particular for the treatment and/or prevention of inflammation and of inflammatory diseases, and to the pharmaceutical, cosmetic and nutraceutical compositions containing same.

Amide derivatives of polycaffeoylquinic acids, process for producing same and uses thereof

Disclosed are glycol esters of dicaffeoylquinic acids, in particular dipropylene glycol esters of dicaffeoylquinic acids (DPG esters of DCQ) and propane-1.3-diol esters of dicaffeoylquinic acids of general formula: wherein Ris a dipropylene glycol radical or a propane 1,3 diol radical, and any two of the radicals R, R, Rand Rare a caffeoyl group, the other two being a hydrogen atom. Also disclosed is a plant extract including same, the method for preparing same and a cosmetic composition including the compounds or extracts, intended for preventing or delaying the appearance of skin ageing effects.

Glycol esters of dicaffeoylquinic acid and uses thereof

An azapeptide compound of Formula I:A-(Xaa)-N(R)&#x2014;N(R)&#x2014;C(O)-(Xaa')-B &#x2003;&#x2003;I.

Azapeptides as CD36 binding compounds

An azapeptide compound of Formula I:A-(Xaa)-N(R)&#x2014;N(R)&#x2014;C(O)-(Xaa')-B&#x2003;&#x2003;I.

An azapeptide derivative of growth hormone releasing peptide (GHRP) of Formula I: A-(Xaa)-N(R)&#x2014;N(R)&#x2014;C(O)-(Xaa')-B which binds to CD 36.

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Ostwald, France

Damien Boeglin