Genspec Sa

Metromol Sa

Damian Twerenbold

Philippe Luginbuhl

Pierre Fran&ccedil;ois Indermuhle

Samuel Wunderli

This invention relates to a quadrupol ion trap mass spectrometer with improved sensitivity for massive molecules by using cryogenic particle detectors as molecule detectors. Cryogenic particle detectors have a mass independent detection efficiency and do not show a decrease of detection efficiency for increasing molecule mass as compared to ionizing detectors which are used in common quadrupol ion trap mass spectrometers.

Quadrupol ion trap mass spectrometer with cryogenic particle detector

The invention relates to a micromechanically produced nozzle for producing reproducibly small drops which consist of a liquid container delimited by a silicon structure and a pyrex structure. The silicon structure is a silicon wafer consisting of a silicon oxide layer (SiO ) and a silicon nitride layer (SI N ). The wafer has a nozzle of silicon oxide (SiO ), which forms a nozzle opening of a liquid container. The liquid is fed into the liquid container through a channel formed in the pyrex structure. A disk made of a piezoelectric material exerts a pressure on the liquid in the container, which passes through the nozzle in the form of a drop.

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Boudry, Switzerland

Damian Twerenbold