Hill's Pet Nutrition, Inc.

Colgate Palmolive Company

Dale S Scherl

Dennis Edward Jewell

Abdul Gaffar

Tao Xu

Samer Al-Murrani

Susan M Herles

Jeffrey Brockman

Kiran Panickar

Jodi Vondran

Chadwick Everett Dodd

Fernando Qvyjt

Albert Avila

Christina Golder

Stephen Davidson

John C Brahms

Kathy L Gross

Christina Khoo

Lori H Szeles

Stuart Shapiro

Ellen Logan

The current invention relates to animal food kibbles having a primarily disc shape and including botanicals such as curcumin. The current invention also relates to methods to reduce oral inflammation in an animal by feeding the animal with the food kibbles. The disc-shaped food kibbles induce a reduction of oral inflammation in the animal compared to control food kibbles having a different shape.

Composition and method for reducing or treating oral inflammation

The present invention encompasses methods and kits employing pattern recognition receptor expression as a measure of systemic health in a subject afflicted with an oral health condition. In particular, the present invention is directed to methods involving measurement of the expression levels of one or more Pattern Recognition Receptors including but not limited to Toll-Like Receptors, myeloid differentiation primary response gene 88 (MyD88), and Nucleotide Binding oligomerization domain containing protein 1 (NOD1), in a companion animal, e.g., a dog or a cat, afflicted with an oral health condition. The described methods enable evaluation of the systemic health of the animal afflicted with an oral health condition by measuring expression levels of the indicated genes as compared to suitable controls.

Pattern recognition receptor expression as a measure of systemic health

Described herein are kits for assessing the calcium oxalate titration test of an animal as well as methods for predicting the risk of calcium oxalate stone formation. Further described herein are methods and compositions for&#x2014;inter alia&#x2014;lowering the specific gravity of urine and lowering the calcium oxalate titration test in felines. In particular, diets and methods utilizing certain amounts and ratios of arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are disclosed herein.

Calcium oxalate titration test kits and pet food compositions

Described herein are methods and compositions for&#x2014;inter alia&#x2014;lowering the specific gravity of urine and lowering the calcium oxalate risk index of in felines. In particular, diets and methods utilizing certain amounts and ratios of arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

Pet food compositions

The present invention encompasses methods and kits employing pattern recognition receptor expression as a measure of systemic health in a subject afflicted with an oral health condition. In particular, the present invention is directed to methods involving measurement of the expression levels of one or more Pattern Recognition Receptors including but not limited to Toll Like Receptors, myeloid differentiation primary response gene 88 (MyD88), and Nucleotide Binding oligomerization domain containing protein 1 (NOD1), in a companion animal, e.g., a dog or a cat, afflicted with an oral health condition. The described methods enable evaluation of the systemic health of the animal afflicted with an oral health condition by measuring expression levels of the indicated genes as compared to suitable controls.

A composition comprising a physically discrete pet food oral intake composition coated with a physically stable film, the film comprising a component which is a) capable of carrying a beneficial agent to a site in the pet wherein the benefit agent is effective in producing a beneficial effect or b) capable of releasing the benefit agent into the mouth or alimentary canal with the benefit agent traveling to a site in the pet wherein the benefit agent is effective in producing a beneficial effect.

Coated pet food composition

Method for increasing the shelf life of a physically discrete dry pet food composition

A method for promoting oral health in a companion animal comprises causing the animal to ingest a composition comprising an oral health-promoting effective total amount of at least one antioxidant.

Method to promote oral health in companion animals

A method is provided for reducing stool odor of a companion animal such as a cat or dog. The method comprises causing the animal to ingest a composition comprising a stool odor reducing effective amount of a zinc ion source, for example zinc acetate.

Method to reduce stool odor of companion animals

A toothbrush includes a support member mounted on a first shaft in the head of the toothbrush. A carrier member is mounted on a second shaft to the support member. The support member is eccentrically mounted so that when its first shaft is rotated the carrier member is moved in an orbital path during the rotation of the support member. The carrier member is freely mounted on its second shaft so that during this orbital movement the carrier member rotates in a random manner. Cleaning elements such as bristles extend outwardly from the carrier member.

Random orbital toothbrush

An oral care composition containing a synergistic antiplaque/antigingivitis combination of a nonionic halogenated diphenyl ether compound such as Triclosan and an extract of Magnolia Officinalas containing honokiol and magnolol.

Synergistic antiplaque/antigingivitis oral composition

An oral antiplaque composition comprising an orally acceptable vehicle and an effective antiplaque amount of 4-alkoxy substituted 2-hydroxy benzophenone compound having the following formula:

Antiplaque oral composition and method

An antibacterial, anti-inflammatory compound for use in oral products, of the formulae: ##STR1## Wherein: R.sub.1 and R.sub.2 are straight chain or branched alkyl substituents or cycloalkyls with one or more alkyl substituents.

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Lawrence, KS, United States of America

Dale S Scherl