Livanova Usa, Inc.

Cyberonics, Inc.

Medtronic, Inc.

Dale G Suilmann

Stephen L Bolea

Robert E Atkinson

Brian D Kuhnley

John P Beck

Sidney F Hauschild

Thomas Barry Hoegh

Bruce J Persson

Wondimeneh Tesfayesus

Paula M Kaplan

Adam K Hoyhtya

Peter R Eastwood

David R Hillman

Daniel A Parrish

Mark R Bosshard

Jason Skubitz

David L Carlson

Heather Diane Orser

Gregory J Loxtercamp

Kenneth J Gutzman

Devices, systems and methods of neurostimulation for treating obstructive sleep apnea. The system is adapted to send an electrical signal from an implanted neurostimulator through a stimulation lead to a patient's nerve at an appropriate phase of the respiratory cycle based on input from a respiration sensing lead. External components are adapted for wireless communication with the neurostimulator. The neurostimulator is adapted to deliver therapeutic stimulation based on inputs.

Obstructive sleep apnea treatment devices, systems and methods

An implantable neurostimulation system comprises a stimulation delivery lead and a neurostimulator. The stimulation delivery lead is coupled to an electrode. The neurostimulator is adapted to deliver a neurostimulation signal to the subject and comprises a microprocessor. The microprocessor is programmed to identify a stimulation operating window for the therapy including a first threshold and a second threshold. The second threshold comprises an awake level and an asleep level. Identifying the stimulation operating window comprises titrating a stimulation setting of the neurostimulator while the subject is awake until the first threshold and the awake level of the second threshold are identified. Identifying the stimulation operating window further comprises subsequently repeating the step of titrating the stimulation setting of the neurostimulator while the subject is asleep until the asleep level of the second threshold is identified.

An example method for controlling delivery of electrical stimulation therapy includes maintaining, by one or more processors of a medical device configured to deliver electrical stimulation to a patient, a counter tied to a clock used by the medical device to deliver the electrical stimulation to the patient; and obtaining, by the one or more processors, one or more representations of sensed electrical signals for the patient that are referenced to counts of the counter. In this example, the method also includes identifying, based on the one or more representations of the sensed electrical signals for the patient, a count of the counter at which stimulation is to be delivered to the patient; and delivering, by the medical device and to the patient, electrical stimulation based on the identified count of the counter.

Precision delivery of electrical stimulation

Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.

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Elk River, MN, United States of America

Dale G Suilmann