Cornell Research Foundation Inc.

Basf Aktiengesellschaft

Dale E Bauman

Walter R Butler

Angelika-Maria Pfeiffer

Euridice Castaneda-Gutierrez

Michael De Veth

R Dean Boyd

Mark A McGuire

P Yvan Chouinard

Mikko Griinari

Kris Sejrsen

Mark A Animal & Veterinary Science Dpt Mcguire

P Yvan Dépt Des Sciences Animales Chouinard

Mikko Valio Inc R & D Centre Griinari

This invention provides methods for improving reproductive performance of lactating dairy cows and other mammals. The method in the case of cows comprises feeding to the cows, a composition comprising conjugated linoleic acids (CLAs), cis-9, trans-11 and trans-10, cis-12. When these CLAs are fed daily to dairy cows starting at or prior to calving, and continued after parturition, an improvement in reproductive performance is observed.

Method of enhancing reproductive function of mammals by feeding of conjugated linoleic acids

The present invention alters mammary synthesis of fat to improve milk quality. These changes in milk composition represent improvements in nutritional quality consistent with contemporary dietary recommendations. Of special importance is the disclosure of new data relating to specific conjugated linoleic acids (CLA), potent naturally occurring anti-carcinogens. In the course of an investigation to enhance milk content of conjugated linoleic acid, it was discovered that abomasal infusion of a single TFA isomer caused a marked milk fat depression. This observation was unexpected because the prior art has consistently shown that body fat and milk fat always show reciprocal changes in lactating cows and indicated that CLA's generally reduced body fat in growing animals. The current disclosure demonstrates that an increase in milk fat content of a specific TFA isomer, trans-10 C,. (Griinari et al., 1997, 1998) causes MFD. This observation is in conflict with the prior art that taught that an increase in total TFA caused MFD. These results are applicable to other domestic lactating mammals (e.g., pigs). Upon the infusion of CLA, a portion of the CLA is transferred to the mammary gland and incorporated into milk fat. Hence, the methods disclosed increase the levels of CLA found in milk, thereby improving the nutritional benefits to human health associated with CLA.

Method of altering nutritional components of milk produced by a lactating animal

This invention relates to deliberately increasing growth hormone in swine during the last 2 weeks of pregnancy through a 3 week lactation. This has the effect of increasing fetal energy storage during late pregnancy which resulted in the newborn piglets having marked enhancement of the ability to maintain plasma concentrations of glucose and free fatty acids when fasted after birth. Likewise, treatment of the sow during lactation results in increased milkfat in the colostrum and an increased milk yield. These effects are important in enhancing survivability of newborn pigs and weight gain prior to weaning.

Use of growth hormone to enhance porcine fetal energy and sow lactation

Use of growth hormone to enhance porcine weight gain

This invention relates to the administration of growth hormone to a ruminant between about the onset of puberty to about first parturition, thereby increasing the quantity of mammary parenchyma, resulting in increased milk production during subsequent lactations.

Use of growth hormone to enhance ruminant mammary development

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Ithaca, NY, United States of America

Dale E Bauman