Seoul National University

Lemonex Inc.

Snu Rdb Foundation

Dal-Hee Min

Cheolhee Won

Jieon Lee

Soo-Ryoon Ryoo

Sejin Park

Seongchan Kim

Yeajee Yim

A method for introducing a foreign gene into a cell according to an embodiment of the present disclosure can easily identify foreign gene introduction by detecting whether there is fluorescent emission or not, and can reduce influence of additional elements other than a target gene since any reporter gene or selectable marker is not required. Further, the inventive method does not need an additional sampling process and therefore may implement a relatively accurate and simple screening process.

Method for confirming introduction of foreign gene into cells and method for manufacturing introduction foreign gene into cells

A composition includes porous silica particles to carry a cell fate modulating factor therein. A method for modulating cell fate includes treating various cells with the composition. The cell fate modulating factor is delivered to a stable target receptor, toxicity to subject cells for delivery may be reduced, a fate of the subject cells can be controlled through sustained release of at least 99 wt. % of the cell fate modulating factor.

Composition comprising porous silica particles carrying a cell fate modulating factor

A quencher containing water-soluble polymer-conjugated nanomaterial effectively quenches the fluorescence of a fluorescent material-conjugated probe. In addition, a composition including the quencher and a fluorescent material-conjugated probe can detect a target material existing at a low concentration, and thus can be favorably used as a composition or kit for providing information necessary for the detection of a biomaterial or the diagnosis of a disease.

Quencher containing water soluble polymer-conjugated nanomaterial and use thereof

The present invention relates a composition, including an RNA probe which contains a fluorescence material absorbed in graphene oxide, for detecting a nucleic acid, and to a method for detecting a nucleic acid using the composition. By means of the composition and the method, the presence and expression pattern of a target nucleic acid in a sample or a cell can be observed in real time, and a plurality of target nucleic acids can be detected in multitude.

Composition for detecting nucleic acid and method for detecting nucleic acid using same

The present invention relates a kit for detecting a nucleic acid and a method of detecting a nucleic acid for enabling a multiplexed-detection and real-time detection of a target nucleic acid by using properties of a graphene oxide.

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Seoul, South Korea

Dal-Hee Min