Fujisawa Pharmaceutical Company, Ltd.

Daizo Morino

Ikuo Ueda

Koichi Takimoto

Masaaki Matsuo

Kiyoshi Tsuji

Hiroyuki Okumura

An antithrombotic compound of the formula: ##STR1## wherein R.sup.1 is halogen,

Thiazolopyridine compounds, processes for the preparation thereof and

Compounds of the formula ##STR1## are disclosed wherein

Mono or dinitroxyalkyl pyridines and vasodilating compositions

The present invention relates to novel benzhydrylpiperazine derivatives having anti-allergic activities, the preparation of these derivatives, pharmaceutical compositions comprising the same, and to a method of using these compounds therapeutically in the treatment of allergic symptoms in human beings and animals. These benzhydrylpiperazine derivatives have the follow formula: ##STR1## wherein A is a lower alkylene, Z is a benzhydryl optionally substituted with halogen, and

Benzhydrylpiperazine derivatives, processes for the preparation thereof

The invention relates to novel dihydropyridine derivatives of vasodilating activity of the formula: ##STR1## in which R.sup.1 is aryl selected from the group consisting of phenyl, tolyl, xylyl, cumenyl and mesityl which may have one or more substituents selected from the group consisting of halogen, nitro, hydroxy, carboxy and lower alkoxy, or a heterocyclic group containing at least one hetero atom selected from the group consisting of oxygen, nitrogen and sulfur,

Vasodilating trinitratoalkyl esters of 2-cyano-1,4-dihydropyridines

This invention relates to pyridylalkyl nitrate compound and a salt thereof. More particularly, it relates to a new pyridylalkyl nitrate compound and a pharmaceutically acceptable salt thereof which have vasodilating activities, to process for the preparation thereof, and to a pharmaceutical composition comprising the same for therapeutical treatment of cardiovascular disorder in human being.

Growing community of inventors

Matsubara, Japan

Daizo Morino