Nissan Chemical Industries Limited

Daisuke Saito

Satoshi Nakano

To provide a novel method for producing an isothiocyanate compound having a carboxyl group(s) from the corresponding amino compound having a carboxyl group(s). A method for producing an isothiocyanate compound which has a carboxyl group(s) and is represented by the formula (2). And the method comprises reacting an amino compound which has a carboxyl group(s) and is represented by the formula (1) (wherein A is e.g. a Caromatic hydrocarbon group or a Csaturated hydrocarbon group, and B is e.g. a single bond, a Caromatic hydrocarbon group or a Csaturated hydrocarbon group), in a solvent, with carbon disulfide (CS) and then with a halogen as a simple substance. 

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Funabashi, Japan

Daisuke Saito