Tokyo Metropolitan Institute of Medical Science

Tokyo Metropolitan Organization for Medical Research

Daisuke Nishizawa

Kazutaka Ikeda

Kenichi Fukuda

Ichiro Sora

Masakazu Hayashida

The present invention provides a method for evaluating (predicting, etc.) an individual difference (the tendency of every individual) in terms of drug sensitivity and disease vulnerability, comprising using a gene polymorphism of a cyclic AMP responsive element binding protein gene or the like. The method for evaluating drug sensitivity and the method for evaluating disease vulnerability according to the present invention comprise associating a gene polymorphism of a cyclic AMP responsive element binding protein gene or a haplotype constituted by the gene polymorphism with the drug sensitivity and disease vulnerability of an individual.

Method for evaluating drug sensitivity and disease vulnerability by analyzing cyclic AMP responsive element binding protein gene

A method of evaluating drug sensitivity or disease vulnerability, includes linking a gene polymorphism in a GIRK channel gene or a haplotype comprising the gene polymorphism to individual drug sensitivity or individual disease vulnerability.

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Tokyo, Japan

Daisuke Nishizawa