Hitachi High-Tech Corporation

Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

Daisuke Ebihara

Shinya Matsuoka

Taku Sakazume

Makoto Nogami

Yuichiro Hashimoto

Yoshihiro Yamashita

Shigeki Matsubara

Kenta Imai

Yuzuru Shimazaki

Takeshi Yokokawa

Takayuki Sugime

Tooru Inaba

Ruochi Hsu

A pretreatment method of an automatic analyzer, in which pretreatments of a plurality of substances to be measured can be performed by a series of treatments using a plurality of magnetic beads that can bind to the plurality of substances to be measured, is achieved. In the pretreatment method of an automatic analyzer, a magnetic bead is added to a sample containing a substance to be measured, the substance to be measured is bound to the magnetic bead, the magnetic bead is extracted from the sample, and the substance to be measured is separated from the magnetic bead by an eluate. A plurality of magnetic beads that bind to a plurality of types of substances to be measured are added to a sample, and the plurality of types of substances to be measured are extracted from the magnetic bead by an eluate.

Pretreatment method of an automatic analyzer

Provided is an automatic analysis device and an analysis method which are capable of reliably detecting an abnormality in a dispensing amount of a solution such as a specimen or a reagent to be dispensed and suppressing a decrease in analysis accuracy. Included are a specimen dispensing mechanismthat dispenses an analysis target specimen in a reaction vessel, a reagent dispensing mechanismthat dispenses another dispensing object different from the specimen in the reaction vessel, and a mass analyzing unitthat detects and analyzes a specific component in a reaction solution in which a specimen dispensed into the reaction vesseland another dispensing object are mixed to each other, in which it is determined whether a dispensed liquid amount of the another dispensing object is abnormal or not, based on a detection result of a standard substance for dispensing inspection which has been added in advance to the another dispensing object, which is detected at the same time with the detection of the analysis target component of the specimen in the reaction solution in the mass analyzing unit

Automatic analysis device

Provided is an automatic analysis technique that prevents liquid contained in a reaction container from locally contacting with liquid added afterward and has less occurrence frequency of equipment malfunction and high performance. An automatic analyzer () includes: a reaction container disk () that holds a reaction container (); a stirring mechanism () that stirs liquid contained in the reaction container () in a non-contact manner; a carrying mechanism () that carries the reaction container () between the reaction container disk () and the stirring mechanism (); a reagent disk () that holds a reagent container (); and a reagent dispensing mechanism () that suctions and discharges a reagent contained in the reagent container (), the stirring mechanism () is provided at a position where the reagent dispensing mechanism () discharges the reagent, and the reagent dispensing mechanism () discharges the reagent, which is sucked from the reagent container (), to the reaction container () installed in the stirring mechanism ().

Automatic analyzer and analysis method

The objective of the present disclosure is to provide a technique for reducing a quantity of magnetic particles remaining on a reaction vessel wall surface in a cleaning step for reducing, in a stepwise manner, an amount of a magnetic particle solution in the reaction vessel. The automated analysis device according to the present disclosure causes an agitating mechanism to operate in such a way that a magnetic substance remaining on the wall surface of the vessel in the previous cleaning step is captured by a cleaning solution in the next cleaning step.

Automated analysis device

An analysis device having a liquid chromatograph prevents a plurality of streams from being unusable at the same time Whether a usable stream is 0 or not among streams 1, 2, and 3 is determined. In a case where none of the streams is usable, the control unit skips a sample introduction in the cycle; and where there is one usable stream in the cycle, the stream is used. In a case where there are multiple streams that are usable in the cycle, and there are multiple streams of which the remaining number of uses of a separation column is the minimum, the stream having the smallest stream number is used; and where there is one stream of which the remaining number of uses of a separation column is the minimum, the stream to which the separation column having the minimum remaining number of uses is connected and used.

Analysis device having a liquid chromatograph and method for analyzing a liquid chromatograph

In order to aspire to higher sensitivity in an automatic analysis device, it is important to prevent the mixing of dust and the like in a reaction part in which a sample and a reagent react. The present invention presents an automatic analysis device that is provided with a configuration for making the pressure inside a specific block in the device such as a reaction part, or inside the device become positive. By making the pressure become positive and forming an air flow that flows out from the inside of the reaction part or the device, it is possible to limit, to a certain amount or less, the amount of dust penetrating into the reaction part.

Growing community of inventors

Tokyo, Japan

Daisuke Ebihara