Wyeth

American Home Products Corporation

Dahui Zhou

Gary Paul Stack

Richard Eric Mewshaw

Ping Zhou

Jonathan Laird Gross

Deborah Ann Evrard

Hong Gao

Adam Matthew Gilbert

Magda Asselin

Kristin L Meagher

Amedeo A Failli

Gavin David Heffernan

Nicole T Hatzenbuhler

Susan Christman Croce

Marla Jean Williams

Aranapakam Madumbai Venkatesan

Compounds of Formula 1 or pharmaceutically acceptable salts thereof are provided: which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

Dihydrobenzofuranyl alkanamine derivatives and methods for using same

Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as premenstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans

Compounds of formula I or pharmaceutically acceptable salts thereof are provided: wherein each of R, R, R, R, R, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

Benzofuranyl alkanamine derivatives and uses thereof

Compounds of formula I or pharmaceutically acceptable salts thereof are provided: wherein each of R, R, R, R, y, m, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

Chromane and chromene derivatives and uses thereof

Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

Quinoline 3-amino chroman derivatives and compositions containing such compounds are disclosed. Methods for using the quinoline 3-amino chroman derivatives and compositions containing such compounds in the treatment of serotonin disorders are disclosed. Also disclosed are processes for preparing quinoline 3-amino chroman derivatives.

Quinoline 3-amino chroman derivatives

Compounds of the formula I: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive-compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

Antidepressant arylpiperazine derivatives of hetrocycle-fused benzodioxans

Aryloxy piperidinyl derivatives for the treatment of depression

Aryloxy piperidinyl indoles for treating depression

Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression

Compounds are provided which have the following formula:

3,4-Dihydro-2H-benzo&lsqb;1,4&rsqb;oxazinyl-methyl)-&lsqb;3-(1H-indol-3yl)-alkyl&rsqb;- amines

Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which comprise

Compounds useful for alleviating symptoms of depression are provided which have the following formula:

N-arloxyethyl-alkylamines for the treatment of depression

Compounds useful for alleviating symptoms of depression are provided which have the following formula: wherein:

Growing community of inventors

East Brunswick, NJ, United States of America

Dahui Zhou