Solvay Pharmaceuticals, Gmbh

Beecham-wuelfing Gmbh & Co. Kg

Kali-chemie Pharma Gmbh

Beecham-wuelfing Gmbh & Co.

Dagmar Hoeltje

Josef Messinger

Lechoslaw Turski

Dieter Ziegler

Michael Weske

Axel Pahl

Yvan Fischer

Yasmin Karimi-Nejad

Hrissanthi Ikonomidou

Dietrich Thielke

Katrin Michaelis

Constanze Hoefer

Ulf Preuschoff

Christian Eeckhout

Jochen Antel

Harald Waldeck

Michael Wurl

Dirk Thormaehlen

Emil Finner

Ljerka Jozic

Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula I, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.

Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them

Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them

Compounds having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity corresponding to the formula 1, wherein the substituents R, R, Rand Rhave the meanings given in the description and also pharmaceutical compositions containing these compounds, in particular pharmaceutical compositions suitable for treating or inhibiting cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.

Ring-contracted N-demethyl-N-isopropyl-erythromycin-A-spiroacetal compounds corresponding to formula I ##STR1## having gastrointestinally effective motilin-agonistic properties and the preparation thereof.

10, 13, 15-trioxatricyclo �9.2.1.1..sup.9.6 !-pentadecan one

Compounds with neutral endopeptidase (NEP) inhibitory activity corresponding to the formula I ##STR1## in which R.sup.1 is a lower alkoxy-lower-alkyl group whose lower alkoxy radical is substituted by a lower alkoxy group, or a phenyl-lower-alkyl or phenyloxy-lower-alkyl group which can optionally be substituted in the phenyl ring by lower alkyl, lower alkoxy or halogen, or a naphthyl-lower-alkyl group,

Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid

Ring-contracted N-demethyl-N-isopropylerythromycin A derivatives with gastrointestinally effective motilin-agonistic properties, a method for preparing such compounds, and pharmaceutical compositions containing them.

4,13-dioxabicyclo[8.2.1]tridecenone compounds and pharmaceutical

A compound of formula (I) or a pharmaceutically acceptable salt thereof; ##STR1## wherein: R.sub.1 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or halogen;

Certain 6,7,8,9-tetrahydropyrido[1,2-.alpha.]indoles and their use for

A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein: R.sub.1 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or halogen;

Tryptamine compounds, and methods of cerebrovascular treatment therewith

A pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein: R.sub.1 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or halogen;

Pyrido[1,2-a]indoles and their use as CNS agents

A compound of the formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein: R.sub.1 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or halogen;

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Gehrden, Germany

Dagmar Hoeltje