Korea Research Institute of Bioscience and Biotechnology

Da Jung Ji

Kyung Seop Ahn

Jae Wha Kim

Sei Ryang Oh

Ho Bum Kang

Ok-Kyoung Kwon

Hee Gu Lee

Hyun Woo Oh

Seung Ho Kim

Hyuk Hwan Song

Joo Heon Kim

Jae Sung Song

Jae Jong Go

Jang Mi Sun

Jang Mi Son

Byeong Hwa Jeon

Khiev Piseth

The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.

Daphne genkwa extracts, and pharmaceutical composition containing fractions of the extracts or compounds separated from the extracts as active ingredients for preventing or treating atopic dermatitis

The present invention relates to a pharmaceutical composition for treating wounds or revitalizing skin comprising theextract, the fractions thereof, or the diterpene compound isolated therefrom as an active ingredient. Theextract may act on epithelial cells to induce PKD1 activity required for improving the reproduction capability of differentiated epithelial cells, and thus may induce the phosphorylation of lower ERK1 and the generation of Cycline D, thus exhibiting an excellent ability to activate the reproduction of damaged skin. Therefore, theextract may be used effectively as an active ingredient in a pharmaceutical composition for treating wounds or reproducing skin, a health food for recovering skin damage or reproducing skin, or a functional cosmetic for inducing skin cell activity.

[object Object]

Growing community of inventors

Daejeon, South Korea

Da Jung Ji