Other

University of Alberta

D Lorne J Tyrrell

Michael Houghton

Babita Agrawal

Rakesh Kumar

Abdolamir Landi

Michael A Joyce

Rakesh Kumar Bhat

Bradley Scott Thomas

Khaled Hassan Sayed Barakat

Adrian Egli

Daire Thomas O'Shea

Deanna Michelle Santer

Atul Humar

Deepali Kumar

Aviad Yaagov Levin

David Broadhurst

The present disclosure provides peptides that modulate an immune response in an individual. The present disclosure provides peptides that modulate cellular responses in vitro. The present disclosure provides compositions comprising the peptides. The peptides and compositions are useful in methods of modulating an immune response in an individual, which methods are also provided.

Immunomodulatory peptides and methods of use thereof

The present disclosure provides methods and compositions that find use in facilitating a diagnosis of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in a subject. The methods and compositions involve measurement of at least one of proteins: IL-16, IL-7, VEGF, CXCL9, CX3CL1, CCL24, CCL19, and CCL11 in a body fluid sample of a subject suspected of having CFS/ME. Levels of one or more of the aforementioned proteins can be used to facilitate a diagnosis of a CFS/ME and/or confirm a diagnosis of CFS/ME. The methods and compositions of the present disclosure also find use in screening subjects for clinical trials and facilitating treatment decisions for a subject.

Methods and compositions in diagnosis of chronic fatigue syndrome/myalgic encephalomyelitis

Disclosed are nucleosides which are useful in diagnosing and treating viral infections, for example, infections caused by hepatitis B virus (HBV), and herpes viruses including Epstein Barr virus.

Antiviral nucleosides

Growing community of inventors

Edmonton, Canada

D Lorne J Tyrrell