Teknimed

Teknimed S.a.

Teknimed Sas

Arkema France

Université Paul Sabatier (toulouse Iii)

Cyril Sender

Michel Glotin

Alain Leonard

Gautier Halbin

Nouredine Sahraoui

Carole Leonard

Claudine Lavergne

Olivier Lignon

Benoit Donazzon

Colette Lacabanne

Julien Iehl

Benoît Donazzon

Alain Bernes

The invention relates to the field of bioresorbable or non-bioresorbable bone substitutes to be implanted in humans in order to reconstitute the bone supply by replacing lost bone substance. More particularly, the invention concerns a device that is simple to manufacture and use and comprises a syringe provided with a single-use dose of a polymer which is fluid at the injection temperature while being solid and durable at body temperature.

Bone substitute and independent injection system

A device in the form of a kit for mixing and injecting a bone cement is described, in which a mixing unit and a transfer unit are two units distinct from and independent of each other, with no element in common, and are designed to be connected alternately, that is to say successively, to the same end of a hollow cylindrical body or mixing body of a main module, before this main module is connected to an injection unit via its other end.

Device in the form of a kit for mixing and injecting a bone cement

A system for attaching a piece of osteosynthesis equipment against a bone tissue includes at least a screw, and a screwdriver having a handle extended by a rod with an adapter to engage the screw. A portion of the guide member of the screwdriver protrudes in front of the end-piece of the screwdriver and extends along or around a portion of the screw to guide the screw in axial translation. The guide member has a front end forming an abutment of the screwdriver against the surface of the piece of osteosynthesis equipment on completion of a predefined depth of screwing of the screw into the bone tissue. The guide member can be set at a chosen length of extension, corresponding to a predefined depth of insertion of the screw. After insertion, the screw can be severed, and optionally fused with the piece of equipment to reinforce the locking of same.

System for attaching a piece of osteosynthesis equipment

The present invention relates to an injectable bone cement for filling bones with mechanical properties equivalent to those of vertebral spongy bone comprising 70 to 99 wt. % of an acrylic polymer combined with an inorganic type radiopaque compound and 1 to 30 wt. % of calibrated hydrophilic flexible solid particles, said calibrated hydrophilic flexible solid particles being chosen from gelatin, poly(glycerol sebacate) or a mixture thereof. A bone cement according to the invention is particularly intended for vertebroplasty, kyphoplasty or cementoplasty.

Bone filling cement

An osteosynthesis device that is both resorbable and radiopaque, produced using gradually degrading materials, includes at least one plate and a set of screws made of resorbable material, in which the plate consists of a composite mixture including i) a resorbable polymer or copolymer compound and ii) an inorganic filler that consists of at least one resorbable ceramic. The screws can be made of resorbable polymer, or of a composite mixture with at least one resorbable ceramic. The device is totally resorbable and radiopaque, and it offers a high level of safety, ensuring a strong and durable fixation of the screws to the plate and in the bone during the entire period needed for bone uniting.

Resorbable and radiopaque device for bone fixation

The invention relates to a system for preparing a polymerized bone cement, including two components reacting with each other when they are mixed to form a solid polymer material. The first component may include a biocompatible acrylic polymer and an initiator capable of initiating a polymerization reaction. The second component may include a monomer capable of dissolving an acrylic polymer, a polymerization activator and a polymerization inhibitor, system in which the second component also includes a biocompatible acrylic polymer dissolved in said monomer, identical or different from the polymer of the first component with an average molar mass greater than 1,000,000 g/mol and a residual initiator content of less than 0.1% to form a gel with determined viscosity. Another object of the invention is a composition designed to constitute the second component of as system used to prepare such cement.

Two-component system for bone cement

The present invention relates to a method for preparing a biodegradable piece for medical use including the steps of:

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Toulouse, France

Cyril Sender