Other

Mcneil-ppc, Inc.

Mcneil-pfc, Inc.

Cynthia M Blase

Manoj N Shah

Garnet E Peck

A buffered aspirin tablet composed of a uniform mixture of aqueous-based polymer coated aspirin, a buffering system and a hydrophillic gel-forming matrix material. The buffering system and matrix material provide a microenvironment on in vitro dissolution of about pH 5. The tablet does not require the use of multilayers and may be prepared by direct compression with conventional equipment.

Buffered matrix aspirin

The present invention relates to an aqueous pharmaceutical suspension composition comprising: from about 0.2% to 20% of a substantially water soluble pharmaceutical active, e.g. acetaminophen; a suspension stabilizing effective amount of xanthan gum and microcrystalline cellulose; an effective amount of taste masking compositions; and water, as well as a process for producing such aqueous pharmaceutical suspensions.

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Lansdale, PA, United States of America

Cynthia M Blase