Becton Dickinson and Company Limited

Curtis M Gosnell

Adrien P Malick

John D Mantlo

Patrick Shawn Beaty

Susan M Kircher

William B Brasso

Liping Feng

Ben Turng

Julie L Rosales

Vanda White

Donald Ray Callihan

Dyan Luper

James Y Zhou

Jeffery H Bruton

John P Douglass

Michael A Brasch

Timothy M Wiles

Raphael Rodolphe Marcelpoil

Trienko Marten Van Der Kaap

Michael Bois

Bas Nieuwenhuis

Donald R Callihan

Shawn Beaty

A system and method for developing applications (Apps) for automated assessment and analysis of processed biological samples. Such samples are obtained, combined with nutrient media and incubated. The incubated samples are imaged and the image information is classified according to predetermined criteria. The classified image information is then evaluated according to Apps derived from classified historical image information in a data base. The classified historical image information is compared with the classified image information to provide guidance on further processing of the biological sample through Apps tailored to process provide sample process guidance tailored to the classifications assigned to the image information.

Application development environment for biological sample assessment processing

Various embodiments disclosed herein provide for reagents and methods for rapidly isolating viable microbial cells, including, from positive blood culture samples. The resulting microbial pellet can be used for both identification and growth-based methods such as antimicrobial susceptibility testing. The buffers described herein may contain a base solution, non-ionic detergents, thiols, and optionally, ammonium chloride. The disclosed methods provide a process for rapidly isolating and concentrating viable microorganism(s) from PBC samples using only one sample preparation tube and centrifugation while removing cellular debris from the mammalian blood cells that may interfere with identification methods.

Formulations and process for isolating viable microorganisms from positive blood cultures

Various embodiments disclosed herein provide for reagents and methods for rapidly isolating viable microbial cells, including, from positive blood culture samples. The resulting microbial pellet can be used for both identification and growth-based methods such as antimicrobial susceptibility testing. The buffers described herein may contain a base solution, non-ionic detergents, thiols, and optionally, ammonium chloride. The disclosed methods provide a process for rapidly isolating and concentrating viable microorganism (s) from PBC samples using only one sample preparation tube and centrifugation while removing cellular debris from the mammalian blood cells that may interfere with identification methods.

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Fallston, MD, United States of America

Curtis M Gosnell