University of Illinois

Curtis L Johnson

Bradley P Sutton

Joseph L Holtrop

John G Georgiadis

A method and system provides an acquisition scheme for generating magnetic resonance elastography displacement data with whole-sample coverage, high spatial resolution, and adequate SNR in a short scan time. The method and system can acquire in-plane and through-plane k-space shots over a volume of a sample divided into a plurality of slabs that each include a plurality of non-adjacent slices to obtain three dimensional multiband, multishot data, can apply multiband radio frequency refocusing pulses to the sample, can acquire navigators before readout, and can correct for non-linear motion errors.

Multiband, multishot magnetic resonance elastography

Magnetic resonance elastography (MRE) is an imaging technique for estimating the stiffness of tissues non-invasively. Shear waves are generated via external mechanical actuation and the tissue imaged with a specially designed MR pulse sequence. The resulting images are used to calculate the underlying properties. The application provides methods for acquiring MRE data using a single shot, echo planar imaging readout. The purpose of the developed sequence is to acquire MRE data using a single-shot, echo-planar imaging readout, avoiding to need for off-line image processing.

Echo-planar imaging magnetic resonance elastography pulse sequence

A method and system provides an acquisition scheme for generating MRE displacement data with whole-sample coverage, high spatial resolution, and adequate SNR in a short scan time. The method and system can acquire in-plane k-space shots over a volume of a sample divided into a plurality of slabs that each include a plurality of slices to obtain three dimensional multislab, multishot data, can apply refocusing pulses to the sample, can acquire navigators after the refocusing pulses, and can correct for phase errors based on an averaging of the navigators.

Three dimensional multislab, multi-shot magnetic resonance elastography

Aspects of the subject disclosure include a system that applies magnetic resonance elastography to a sample to obtain uncorrected k-space data where the magnetic resonance elastography utilizes a multi-shot spin-echo sequence with variable density spiral readout gradients, and adjusts the uncorrected k-space data to corrected k-space data by adjusting a k-space trajectory by shifting a center point for each shot to a new center point according to signal intensity and by adjusting a phase for each shot based on a phase offset that is determined according to the signal intensity.

Growing community of inventors

Urbana, IL, United States of America

Curtis L Johnson