Kimberly-clark Worldwide, Inc.

Chemtura Corporation

Curt Sayre

John Gavin MacDonald

Xuedong Song

Ning Wei

Jason Lye

Stephanie Michelle Martin

Kimberlee Fay Thompson

Zach Hansen

David Rouse

Rebecca Covington

Steven Dietz

Brian Holliday

Anna McLeroy

A method for detecting a microorganism or class of microorganisms is provided. More specifically, the method employs an array that contains a plurality of discrete regions (referred to as 'addresses') spaced apart on a solid support in a predetermined pattern. The addresses are selected so that the array provides a distinct spectral response (e.g., pattern of colors) or 'fingerprint' for a particular microorganism or class of microorganisms. For example, the array may provide a certain spectral response in the presence of one microorganism or class of microoryanisms (e.g., gram-negative bacteria), but provide a completely different spectral response in the presence of another microorganism or class of microorganisms (e.g., gram-positive bacteria). Detection of the spectral response provided by the array may thus allow for differentiation between microorganisms.

Array for rapid detection of a microorganism

Dispensing device

A flow-through assay for detecting the quantity of an analyte residing in a test sample is provided. The flow-through assay contains a porous membrane that is in fluid communication with probe conjugates that contain a specific binding member and a detectable probe. The porous membrane also defines a detection zone and a calibration zone. The calibration zone contains a polyelectrolyte substantially non-diffusively immobilized on the porous membrane. The polyelectrolyte is capable of generating a detectable calibration signal that can be readily compared (visually, quantitatively, and the like) to a detection signal to determine the amount of analyte in the test sample.

Polyelectrolytic internal calibration system of a flow-through assay

Growing community of inventors

Atlanta, GA, United States of America

Curt Sayre