Depomed, Inc.

Jazz Pharmaceuticals Ireland Limited

Cuiping Chen

Bret Berner

Clark Patrick Allphin

Katayoun Zomorodi

Gunjan H Junnarkar

Mark Eller

Dan Chen

Franck Skobieranda

Amanda Leigh Sterkel

Patricia Chandler

Roman Skowronski

The present disclosure relates to methods of treating idiopathic hypersomnia with oxybate, preferably a mixture of salts of oxybate (a mixed salt oxybate).

Methods of treating idiopathic hypersomnia

Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of making the pharmaceutical compositions and formulations, and methods of their use for the treatment of sleep disorders such as apnea, sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus.

Gamma-hydroxybutyrate compositions and their use for the treatment of disorders

Gastric retentive dosage forms for sustained release of acamprosate are described which may allow once- or twice-daily dosing for both acute and long-term treatment of a disorder including alcohol dependence, tinnitus, sleep apnea, Parkinson's disease, levodopa-induced dyskinesias in Parkinson's disease, Alzheimer's disease, Huntington's disease, Amyotrophic lateral sclerosis, Cortical spreading depression, migraine, schizophrenia, anxiety, tardive dyskinesia, spasticity, multiple sclerosis, various types pain, or binge eating. Methods of treatment using the dosage forms and methods of making the dosage forms are also described.

Gastric retentive dosage forms for extended release of acamprosate into the upper gastrointestinal tract

Growing community of inventors

Palo Alto, CA, United States of America

Cuiping Chen