Richter Gedeon Vegyeszeti Gyar Rt

Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Egyt Gyogyszervegyeszeti Gyar

Egis Gyogyszergyar Rt.

Richter Gedeon Vegyeszeti Gmbh

Csaba Szantay

Lajos Szabo

Gyorgy Kalaus

Laszlo Szporny

Egon Karpati

Tibor Keve

Lajos Dancsi

Janos Kreidl

Bela Kiss

Laszlo Czibula

Andras Nemes

Janos Sapi

Katalin Honty

Bela Stefko

Ferenc Drexler

Lajos Novak

Tibor Acs

Gabor Kovacs

Istvan Szekely

Sandor Virag

Elemer Ezer

Gyorgy Fekete

Maria Farkas Nee Kirjak

Sandor Eckhardt

Janos Sugar

Istvan Hegedus

Andras Vedres

Eva Palosi

Gyorgy Hajos

Erzsebet Lapis

Istvan Stadler

Istvan Tibor Toth

Gyorgy Visky

Vilmos Simonidesz

Eszter Dezseri

Maria Incze

Tibor Cs

Erzsebet Kanyo

Agoston David

Gabor Blasko

Istvan Laszlovszky

Zsolt Szombathelyi

Laszlo Toke

Aniko Gere

Istvan Tomoskozi

Maria Zajer Nee Balazs

Marianna Lovasz Nee Gaspar

Csaba Kuthi

Lajos T Nagy

Sandor Gorog

Eva Somfai

Laszlo Pap

Andras Szego

Erik Bogsch

Katalin Csomor

Adam Sarkadi

Attila Kis-Tamas

Karola Jovanovics

Csaba Lorincz

Arpad Kiraly

Katalin Nogradi

Lilla Forgacs

Gabor Megyeri

Lilla Forgach

Judit M Meszaros Nee Brill

Bela Rosdy

Gyongyver Kiraly Nee Soos

Andrea Toth

Tamas Mester

Gyula Simig

Gabor Gigler

Bela Hegedus

Sandor Farkas

Gyula Sebestyen

Ferenc Trischler

Judit Matuz

Janos Galambos

Dora Groo

Gyorgy Domany

Zoltan Tuba

Judit Laszy

Daniel Bozsing

Peter S Kormoczy

Lajos Kovacs

Katalin Szemeredi

Pal Vittay

Sandor Szabo

Andras Egyed

Maria Gazdag

Margit Csorgo

Ida Deutsch Nee Juhasz

Geza Galambos

Ferenc Auth

Eva Werkne Papp

Judit Nagyne Bagdy

Miklos Toth

Zsuzsanna Aracs Nee Tischler

Gyorgy Dobo

Bela Benke

Gyorgy Ferenczy

A new process is disclosed for the synthesis of fluconazole monohydrate and for crystal modifications of fluconazole which comprises the step of 

Process for preparing monohydrate and crystal modifications of fluconazole

2-methoxyphenylpiperazine derivatives

Trans apovincaminic acid ester derivatives

This invention relates to new oxaindene derivatives, a process for the preparation thereof and pharmaceutical compositions comprising the same. The compounds according to the invention are characterized by the general formula (1) ##STR1## wherein R.sup.1 represents lower C.sub.1-4 alkyl, lower C.sub.1-4 alkoxy or lower C.sub.3-6 cycloalkyl,

Oxaindene derivatives and process for the preparation thereof

Substituted propane-2-OL derivatives

Biologically active eburnamenine derivatives, pharmaceutical

The invention relates to novel combined compositions for combatting plant, animal and sanitarian as well as forestry, horticultural and warehouse pests. These compositions contain a pyrethroid-type insecticide as an insecticidally active ingredient and at least one fungicide inhibiting the ergosterol biosynthesis as activity-strengthening agent as well as optionally piperonylbutoxide and other additives. The advantages of the compositions according to the invention consist therein that the activity-strengthening substances used are fungicidal agents widely used and have an advantageous toxicology. The activity-strengthening agent exerts a synergistic effect together with the pyrethroid-type insecticide. The combinations according to the invention bear an outstanding importance in the protection of stored crops.

Combined compositions

New intermediate compounds are disclosed of the formula I, ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl having 1 to 4 carbon atoms, or acid-addition salts thereof of formula Ib, ##STR2## wherein X represents an acid residue, and a process for the preparation of the intermediate compounds.

Racemic and optically active octahydro-indolo(2,3-a) tetrahydropyranyl

The invention relates to a new process for preparing 6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine of the formula (I), ##STR1## which comprises reacting a pyrimidine derivative of the general formula (II), ##STR2## wherein R.sub.1 stantds for hydrogen or a ##STR3## group, wherein R means a C.sub.1-6 alkyl group or an aryl group optionally substituted by halogen;

Preparation of

The invention relates to new racemic and optically active 1,12b-disubstituted octahydroindolo[2,3-a]quinolizine derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and represent hydrogen, halogen, nitro, alkyl having from 1 to 6 carbon atoms, alkoxy having from 1 to 6 carbon atoms or hydroxyl,

1,12-disubstituted octahydroindolo[2,3-]quinolizine derivatives,

The invention relates to a new process for preparing novel racemic and optically active 9- or 11-nitroapovincaminic acid derivatives of the general formula (I) ##STR1## wherein R stands for a --CO--X group, wherein X means a halogen atom; or

Nintrovincaminic acid derivatives having pharmaceutical utility

The invention relates to the new (-)-1.beta.-ethyl-1.alpha.-hydroxymethyl-1,2, 3,4,6,7,12,12b.alpha.-octa-hydroindolo[2,3-a] quinolizine of the formula (I) ##STR1## and acid addition salts thereof. According to another aspect of the invention there is provided a process for the preparation of the compound of formula (I) and acid addition salts thereof by resolution of the corresponding racemic compound and optionally by subsequent hydrolysis and/or salt formation. The compound of formula (I) shows a remarkable peripheral vasodilating and antihypoxial activity. Pharmaceutical compositions comprising it as active ingredient are also within the scope of the invention.

(-)-1.beta.-ethyl-1.alpha.-hydroxymethyl-1,2,3,4,6,7,12,

The invention relates to new 1,2,3,4,6,7,12,12b-octahydroindolo[2,3,-a]quinolizin-1-yl-alkanecarboxylic acid amides of the formula (I), ##STR1## wherein R.sub.1 and R.sub.2 stand independently for a hydrogen or halogen atom, or a hydroxyl, nitro or C.sub.1-4 alkoxy group;

Octahydroindolo[2,3-a]quinolizin-1-yl-alkanecarboxylic acid amines and

A pyrimidine derivative of the formulae (Ia), (Ib) and (Ic), ##STR1## wherein R stands for an alkyl group group with 1 to 6 carbon atoms or an aryl group optionally substituted by halogen atom; and

Pyrimidine derivatives and process preparing the same

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Budapest, Hungary

Csaba Szantay