Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Ramot Univ. Auth. for Applied Research and Industrial Development Ltd.

Csaba Koncz

Jeff Schell

Nicolai Strizhov

Baruch Sneh

Thomas Altmann

Aviah Zilberstein

Jaideep Mathur

Menachem Keller

Miklos Szekeres

A method of gene synthesis is disclosed. The gene synthesis method permits the codons of [m] natural gene to be changed to allow preferential transcription and translation of the synthetic gene in transgenic organisms. The method utilizes a combination of enzymatic and chemical synthesis of DNA and significantly reduces the cost, time and number of steps required for construction of synthetic genes.

Gene synthesis method

The present invention relateds to a synthetic version of a gene isolated from Bacillus thuringiensis encoding an insectidical crystal protein designated CryIC, plants transformed with the gene, and the insecticidal crystal protein toxin expressed by the gene, all of which are used to control insects of the Spodoptera species as well as those of the Mamestra species.

Synthetic Bacillus thuringiensis cryic gene encoding insect toxin

The invention describes nucleic acid molecules encoding cytochrome P450-t proteins involved in the brassionosteroid synthesis in plants, transgenic plant cells and plants containing such nucleic acid molecules as well as processes for the identification of other proteins involved in brassinosteroid synthesis and processes for the identification of substances acting as brassinosteroids or as brassinosteroid inhibitors in plants.

Nucleic acid molecules encoding cytochrome P450-type proteins involved

Growing community of inventors

Koln, Germany

Csaba Koncz