Sicpa Holding Sa

Olivetti S.p.a.

Cristina Panciatichi

Oriana Rossotto

Davide Ciampini

Lucia Giovanola

Duccio Spartaco Sassano

Tazio Sandri

Giacomo Mabritto

The present invention relates to an adhesive composition comprising (1) at least one polyol tri(meth)acrylate monomer selected from the group consisting of ditrimethylolpropane triacrylate (DiTMPTTA), tris-(2-hydroxyethyl)-isocyanurate triacrylate (THEICTA), dipentaerythritol triacrylate (DiPETA), ethoxylated trimethylolpropane triacrylate (TMPEOTA), propoxylated trimethylolpropane triacrylate (TMPPOTA), ethoxylated pentaerythritol triacrylate (PETEOIA), propoxylated glyceryl triacrylate (GPTA), pentaerythritol triacrylate (PETA), trimethylolpropane triacrylate (TMPTA) and modified pentaerythritol triacrylate, triethyleneglycol trimethacrylate (TIEGTMA), tetraethyleneglycol trimethacrylate (TTEGTMA), polyethyleneglycol trimethacrylate hexane trimethacrylate (HTTMA) ethoxylated bisphenol A trimethacrylate, and trimethylolpropane trimethacrylate (TMPTMA), (2) at least one polyalkylene glycol mono(meth)acrylate monomer selected from the group consisting of polypropylene glycol monomethacrylate, polyethylene glycol monomethacrylate, polyethylene glycol-polypropylene glycol monomethacrylate, polypropylene glycol-monoacrylate, polyethylene glycol monoacrylate, polypropylene glycol-polytrimethylene monoacrylate, polyethylene glycol-polytetramethylene glycol monomethacrylate, methoxypolyethylene glycol monomethacrylate, yerfluoroalkylethyl-polyoxyalkylene monomethacrylate, and combinations thereof, and (3) at least one radical initiator selected from the group of initiators sensitive to UV and/or blue radiation (photoinitiator) and thermal initiators (thermoinitiator). The adhesive composition is used for assembling elements made of plastic materials, like PMMA or SAN, or inorganic materials, like glass or metals, employed for manufacturing of devices for the distribution of containment of biological substances.

Acrylic adhesive for assembling elements contacting biological substances

The present invention relates to acrylic adhesive composition comprising a mixture of at least one polyol tri(meth)acrylate monomer and at least one polyalkylene glycol mono(meth)acrylate monomer for assembling elements made of plastic materials, like PMMA or SAN, or inorganic material, like glass or metals, employed for manufacturing of devices for the distribution or containment of biological substances, like proteins, enzymes, antibodies, antigens, DNA, and the like. The present invention also relates to devices for the distribution or containment of biological substances assembled with the above mentioned acrylic adhesive composition, and particularly thermal or piezoelectric ejecting devices, and biochip microarray, as well as to a method for assembling thereof.

There is described a method for depositing at least one biological fluid onto a surface of a substrate, the method comprising the steps of (i) providing at least one thermal bubble jet printhead loaded with at least one biological fluid, (ii) positioning the printhead next to the substrate, and (iii) supplying the printhead with energy thereby depositing the biological fluid onto the surface. The printhead is supplied with an energy E such that&#x3e;1.6*where Eis the threshold energy of the printhead. There are also described an apparatus for depositing at least one biological fluid onto a surface of a substrate and a microarray obtained by carrying out the depositing method.

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Arnad, Italy

Cristina Panciatichi