Novimmune Sa

Swedish Orphan Biovitrum Ag

Swedish Orphen Biovitrum Ag

Cristina De Min

Fabrizio De Benedetti

Walter Ferlin

Greg Elson

Limin Shang

Emmanuel Monnet

Eric Hatterer

The disclosure relates generally to methods compositions and dosing regimens for treating, preventing and/or delaying the onset or progression of, or alleviating a symptom associated with elevated IFN-&#x3b3; levels.

Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications

Methods and compositions for treating hemophagocytic lymphohistiocytosis (HLH) are provided. The disclosure also relates generally to methods and compositions for diagnosing and treating disorders associated with elevated levels of CXCL9, elevated levels of total IFN&#x3b3;, and other biomarkers. The disclosure also relates to methods of treating, delaying the progression of, or otherwise ameliorating a symptom of a disorder in patients with elevated levels of CXCL9 elevated levels of total IFN&#x3b3;, and other biomarkers using agents that interfere with or otherwise antagonize interferon gamma (IFN&#x3b3;) signaling, including neutralizing anti-IFN&#x3b3; antibodies.

Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of CXCL9 and other biomarkers

This invention relates generally to methods and compositions for diagnosing and treating disorders associated with elevated levels of Toll-like Receptor 4 (TLR4) ligands and other biomarkers. The invention also relates to methods of treating, delaying the progression of, or otherwise ameliorating a symptom of a disorder associated with elevated levels of TLR4 ligands and other biomarkers using agents that interfere with or otherwise antagonize TLR4 signaling, including neutralizing anti-TLR4 antibodies.

Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of TLR4 ligands and other biomarkers

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Geneva, Switzerland

Cristina De Min