Oxtox Limited

Craig Edward Banks

Patrick Robinson Huddleston

Dimitrios Konstantinos Kampouris

Angelo Kotsis

John Parselle

Rashid Olukayoee Kadara

Peter Leslie James McMillan

Peter Leslie James Mcmillan

Peter Leslie Mcmillan

A device combining a fuel-cell-type breathalyzer with an electrochemical saliva drug test. The saliva drug tester comprises a disposable test strip-electrode module assembly and an analyzer module. The saliva is squeezed out of an absorbent swab when the test strip is inserted into the electrode module. The electrode module can also carry information that is read and evaluated by the analyzer, e.g. for verification of the electrode module.

Combination of breathalyser and electrochemical saliva drug test

The invention provides an electrochemical assay for a phenol analyte in a body fluid sample wherein said sample, or fluid therefrom, is contacted with the working electrode of an electrode assembly comprising a working electrode, a counter-electrode, a voltage supply to said working and counter-electrodes and a current meter for determining the current between said working and counter-electrodes, and wherein a first compound capable of reversible oxidation and reduction is disposed at said working electrode, said first compound being capable in either an oxidized or a reduced form of binding to said phenol analyte, characterized in that said first compound in its oxidized or reduced form comprises a group of structure I R1-NH&#x2014;C*&#x2014;(C*&#x2014;C*)&#x2014;C*-QR' (I) (where n is 0 or 1; Q is 0, S, NH or NR&#x2032;; C*&#x2014;(C*&#x2014;C*)&#x2014;C* is a two or four carbon string in a conjugated delocalised electron system optionally substituted by a group comprising R; R is an electron-donating or withdrawing substituent; and R&#x2032; is H or a group R, at least one group R&#x2032; being a group R).

Electrochemical assay

The invention provides a method of assaying for tetrahydrocannabinol in a body fluid. The method includes contacting a sample of body fluid with an imine capable of reacting with tetrahydrocannabinol to yield a quinone imine, and detecting the formation of a quinone imine, where the sample is contacted with the reagent compound at a pH of at least 10.5.

Methods of assaying for tetrahydrocannabinol

The invention provides an assay method for the detection of a primary amine analyze in an aqueous body fluid, which method comprises contacting a sample of said body fluid at a pH below 9.5 with a thiol and an unsaturated cis-dialdehyde and testing for the presence of a pyrrole reaction product.

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Nottingham, United Kingdom

Craig Edward Banks