Pfizer Corporation

Craig Alex Avery

George Stuart Cockerill

Edward Cochrane

James Good

Andrew Joseph Warner

Benzodiazepine derivatives of formula (I): (I) wherein: each of Rand Ris independently H or halo; either (i) T is N, Z is C,andare bonds, andandare absent; or (ii) T is C, Z is N,andare bonds, andandare absent; each of Rand Ris independently halo, —OR, —NRR, —COR, —C(O)OR, —CON(R)or —R; Ris H or halo; each of Rand Ris independently H or a group selected from C-Calkyl, C-Ccycloalkyl, C-Caryl, 4- to 10-membered heterocyclyl and 4- to 10-membered heteroaryl, the group being unsubstituted or substituted; Ris H or C-Calkyl, each Rbeing the same or different when two are present; n is 0 or 1; and one of V, W, X and Y is N or CH and the other three are CH; and the pharmaceutically acceptable salts thereof are inhibitors of RSV and can therefore be used to treat or prevent an RSV infection.

Growing community of inventors

Nottingham, United Kingdom

Craig Alex Avery