Boston Scientific Scimed, Inc.

Boston Scientific Corporation

Courtney Sikes

Mark W Boden

Shrirang V Ranade

Mark Steckel

According to one aspect of the invention, medical devices are provided which contain the following: (a) an interior region that contains at least one degradation promoting agent and (b) an exterior region disposed over the interior region that contains at least one biodegradable polymer and at least one therapeutic agent.

Medical devices for the release of therapeutic agents

A block or graft copolymer includes a first block, and a second block different from the first block, wherein the first block is a poly(lactide-glycolide) copolymer. The polymers may be formulated in compositions with drug components for use in coating medical devices such as stents. Different blocks of the block or graft copolymer degrade in the body at different rates. The drug release profile from the coating is a combination the individual release rates of the different blocks and so can be controlled by controlling the selection and relative amounts of the respective blocks.

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Uxbridge, MA, United States of America

Courtney Sikes