Colgate Palmolive Company

Cortney L Worrell

Ravi Subramanyam

Harsh Mahendra Trivedi

Tao Xu

Ying Yang

Davide Miksa

Ryan Bradley Cameron

Kimberlee Panaligan

Chanda Macias

Yanan Hu

The present invention discloses novel uses of specific menthol-derivative compounds of Formula 1, and compositions thereof, for methods of providing oral and systemic health care benefits, and methods of up-regulating or down-regulating periodontal disease metabolites: Formula 1 wherein, X is an oxygen atom or an NH radical; and R is an unsubstituted or substituted aryl or aliphatic radical. In some embodiments, the oral and systemic health care benefits include biofilm anti-attachment, anti-inflammation, anti-oxidant, anti-bone loss, and anti-microbial benefits. In some embodiments, the periodontal disease metabolites correspond to healthy and/or diseased oral status and allow differential diagnosis of oral health. 

Menthol-derivative compounds and use thereof as oral and systemic active agents

An oral composition for at least one or treating and inhibiting an oral inflammatory condition comprising:

[object Object]

A multi-benefit oral composition is provided. The oral composition is efficacious as an antibacterial, antiplaque, anti-inflammatory, anti-oxidant, and anti-halitosis oral composition. The active ingredient has one or more active compounds from an extract of oregano. The oral composition can be in the form of a mouth rinse; a dentifrice, including toothpaste, gels, powders; animal products; a film; or confectionaries, such as lozenges, and the like. Methods of making and using the oral composition are also provided.

Oregano oral care compositions and methods of use thereof

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Plainfield, NJ, United States of America

Cortney L Worrell