Boehringer Mannheim Gmbh

Roche Diagnostics Gmbh

Dr. Karl Thomae Gmbh

Dr. Karl Tomae Gmbh

Cortina Kaletta

Gunther Jung

Roland Kellner

Friedrich Gotz

Sibylle Berner

Thomas Kupke

Cornelia Kruse-Mueller

Karl-Dieter Entian

Bernd Wieland

Ralf Rosenstein

Germar Engelke

Johannes Augustin

Norbert Schnell

Cora Klein

Christoph Kessler

Joerg Kleiber

Udo Reischl

Ruediger Rueger

Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.

Method for electrochemiluminescent labeling of nucleic acid, use in

A bacterial host is described which is transformed by a plasmid coding for a polypeptide precursor wherein the host comprises a multi-enzyme complex capable of reacting with the expressed polypeptide precursor to produce a polypeptide comprising at least one dehydroamino acid and/or at least one lanthione bridge. A process for producing a polypeptide comprising at least one dehydroamino acid and/or at least one lanthione bridge, such as gallidermin, is also described. A plasmid capable of transforming a bacterial host is additionally described. Also disclosed are recombinant DNA molecules which specify Epi B, Epi C, Epi D, Epi P and Epi Q, enzymes which are involved in the biosynthesis of lantibiotic epidermin.

Biosynthetic process for the preparation of chemical compounds

A bacterial host is described which is transformed by a plasmid coding for a polypeptide precursor wherein the host comprises a multi-enzyme complex capable of reacting with the expressed polypeptide precursor to produce a polypeptide comprising at least one dehydroamino acid and/or at least one lanthionine bridge. A process for producing a polypeptide comprising at least one dehydroamino acid and/or at least one lanthionine bridge, such as gallidermin, is also described. A plasmid capable of transforming a bacterial host is additionally described. Also disclosed are recombinant DNA molecules which specify Epi B, Epi C, Epi D, Epi P and Epi Q, enzymes which are involved in the biosynthesis of lantibiotic epidermin.

DNA encoding and biosynthetic process for the preparation of chemical

Method for immobilizing nucleic acids using modified capture probes

Process for the specific production of nucleic acids based on the principle of transcription in which a promoter oligonucleotide and a template-specific oligonucleotide which can hybridize with it are used as a promoter reagent and a process for nucleic acid detection which is based on this process.

Promotor controlled specific amplification of nucleic acid sequences

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Munich, Germany

Cortina Kaletta